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  1. A psychiatrist hires his mistress to kill his wife, but Lt. Columbo suspects him and investigates. IMDb provides cast, crew, reviews, trivia, plot summary, and more for this 1968 crime drama mystery.

    • (5.6K)
    • Crime, Drama, Mystery
    • Richard Irving
    • 1968-02-20
  2. 20 hours ago · After more than 40 years of hosting the game show, Sajak is taking on a project of a different pace: a starring role in a play called "Prescription: Murder." Per the Hawaii Theatre Center, Sajak ...

    • 3 min
    • Chrissy Callahan
  3. Aug 19, 2015 · A classic Columbo movie from 1968 that introduced the character to a global audience. Read how Lieutenant Columbo outwits a clever psychiatrist who murders his wife and tries to frame his lover.

    • 11 min
  4. Columbo investigates a corporation executive's murder with an exploding cigar box. William Windom, Ida Lupino, Roddy McDowall, Anne Francis and James Gregory guest star.

    • Richard Irving
    • January 1, 1968
    • 99 min
    • columbo prescription murder1
    • columbo prescription murder2
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  5. Prescription: Murder is the first ever episode of Columbo. It first aired on February 20, 1968 and was directed by Richard Irving. The episode stars Peter Falk in his first appearance as Lieutenant Columbo and Gene Barry as the series' first murderer, Dr. Ray Fleming.

  6. Aug 6, 2017 · In a new article format I tackle the 5 most memorable moments from each Columbo episode, starting off with Prescription: Murder. Is your favourite moment here?

  7. www.rottentomatoes.com › m › columbo_prescription_murderColumbo | Rotten Tomatoes

    REVIEWS: 60% The crime thriller Prescription: Murder marks the debut of Peter Falk as Lt. Columbo. Adapted from a stage play a philandering psychiatrist attempts ...

    • Mystery & Thriller
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