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What is the anatomy and physiology of pain?
What does a physiology study tell us about chronic pain?
Which physiological mechanisms explain referred pain?
According to the International Association for the Study of Pain, pain is defined as an “unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage.” There are three types of pain classified by cause.
Jul 24, 2023 · Author Information and Affiliations. Last Update: July 24, 2023. Go to: Pain is likely the most common symptomatic complaint in medicine; an understanding of its pathophysiology is critical to interpreting it in patients. [1] [2] Differentiating between the terms nociception and pain is worthwhile.
- 2023/07/24
In this chapter we review the anatomy and physiology of pain pathways. We also discuss some of the physiological processes that modify the pain experience and that may contribute to the development of chronicity. For obvious reasons, most of this information comes from animal experiments.
- Marian Osterweis, Arthur Kleinman, David Mechanic
- 1987
- 1987
Therefore, pain is not simply inferred or described as nociception – the detection of noxious chemical, thermal or mechanical stimuli. Rather, the perception of pain is founded on the complex integration of physiologic signaling at three major levels: Transduction, Transmission and the Perception of Pain.
- General Overview of Pain
- Pain Mechanisms
- Practical Applications
The most widely accepted and current definition of pain, established by the International Association for the Study of Pain (IASP), is: Although several theoretical frameworks have been proposed to explain the physiological basis of pain, not one theory has been able to exclusively incorporate all aspects of pain perception. The four most influenti...
Determining the most plausible pain mechanism(s) is crucial during clinical assessments as this can serve as a guide to determine the most appropriate treatment(s) for a patient. Therefore, criteria upon which clinicians may base their decisions for appropriate classifications have been established through an expert consensus-derived list of clinic...
Specific classification systems can be useful when diagnosing or classifying pain. The rest of this page focuses on the biopsychosocial model, which encourages clinicians to consider biomedical, psychological and social factors that influence an individual's pain, and the McKenzie Mechanical Diagnosis and Therapy and tissue-based classification sys...
Pathophysiology of Pain. Acute pain, which usually occurs in response to tissue injury, results from activation of peripheral pain receptors and their specific A delta and C sensory nerve fibers (nociceptors). Chronic pain related to ongoing tissue injury is presumably caused by persistent activation of these fibers.
Jan 1, 2013 · The current definition of pain, established by the International Association for the Study of Pain (IASP) in 1986, defines pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of tissue damage, or both.”
