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Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection. It is administered by intravenous infusion. Dextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons.
Monitor CVP as an estimate of blood volume status and a guide for determining dosage. Normal CVP: 5–10 cm H 2 O. Observe for S&S of circulatory overload (see Appendix F). Note: When sodium restriction is indicated, know that 500 mL of dextran 40 in 0.9% normal saline contains 77 mEq of both sodium and chloride.
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- Table of Contents
- What Are IV Fluids?
- Types of IV Fluids
- Crystalloids
- Colloids
- Recommended Resources
- See Also
- References and Sources
Intravenous fluids (IV Fluids), also known as intravenous solutions, are supplemental fluids used in intravenous therapy to restore or maintain normal fluid volume and electrolyte balance when the oral route is not possible. IV fluid therapy is an efficient and effective way of supplying fluids directly into the intravascular fluid compartment, in ...
There are different types of IV fluids and different ways on how to classify them. The most common way to categorize IV fluids is based on their tonicity: 1. Isotonic. Isotonic IV solutions that have the same concentration of solutes as blood plasma. 2. Hypotonic. Hypotonic solutions have lesser concentration of solutes than plasma. 3. Hypertonic. ...
Crystalloid IVsolutions contain small molecules that flow easily across semipermeable membranes. They are categorized according to their relative tonicity in relation to plasma. There are three types: isotonic, hypotonic, and hypertonic.
Colloids contain large molecules that do not pass through semipermeable membranes. Colloids are IV fluids that contain solutes of high molecular weight, technically, they are hypertonic solutions, which when infused, exert an osmotic pull of fluids from interstitial and extracellular spaces. They are useful for expanding the intravascular volume an...
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Here are other nursing pharmacology study guides: 1. Nursing Pharmacology – Study Guide for Nurses Our collection of topics related to nursing pharmacology 2. Pharmacology Nursing Mnemonics & Tips These nursing mnemonics aim to simplify the concepts of pharmacology through the use of a simple, concise guide. 3. Generic Drug Name Stems Cheat Sheet L...
The following are the references and sources for this IV fluid guide that you may find interesting or if you want to further your reading: 1. Berman, A., Snyder, S. J., Levett-Jones, T., Dwyer, T., Hales, M., Harvey, N., … & Stanley, D. (2018). Kozier and Erb’s Fundamentals of Nursing [4th Australian edition]. 2. Dougherty, L., & Lamb, J. (Eds.). (...
Dextran 40 causes marked factor VIII decrease and a greater decrease in factors V and IX than expected from the effects of hemodilution alone. Usually occurs at doses near 1.5 g/kg (15 mL/kg). Observe trauma and major surgery patients for early signs of bleeding complications.
May 1, 2023 · Mechanism of Action. Dextran is a polysaccharide made from natural sources of glucose by bacteria and with 1:6 glucoside links. [4] . It can occur in various molecular weights, such as dextran 40 (40 kDa) and dextran 70 (70 kDa), which are both commonly utilized. [5] .
- Kathleen H. Miao, Kevin B. Guthmiller
- 2023/05/01
Sep 30, 2014 · Dextran Gelatins; Solution concentration 4%, 5% 20%, 25% 6%, 10% pentastarch 6% hetastarch 10% Dextran 40 3% Dextran 60 6% Dextran 70 Molecular weight: 69 100-450 40-70 30-35: Osmolality (mOsm/L) 300: 1.500: 300-326 280-324 300-350: Oncotic pressure (mmHg) 19-30: 74-120: 23-82 20-60 25-42: Plasmatic expansion (%) 70-100: 200-300: 100-160 100 ...
Feb 15, 2024 · Iron dextran is an intravenous iron solution tailored to treat iron deficiency anemia. Oral iron therapy is frequently used for the treatment of iron deficiency anemia. However, certain patients either exhibit inadequate responses to oral iron or encounter difficulties in its administration.
