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  1. www.uptodate.com › contents › locked-in-syndromeLocked-in syndrome - UpToDate

    Nov 2, 2023 · INTRODUCTION. The locked-in syndrome is a catastrophic condition caused most often by ischemic stroke or hemorrhage, affecting the corticospinal, corticopontine, and corticobulbar tracts in the brainstem. Because consciousness and higher cortical functions are spared, patients can sometimes communicate through eye movements.

    • What Are The Signs and Symptoms of Locked-In Syndrome?
    • Can You Feel Pain with Locked-In Syndrome?
    • What Causes Locked-In Syndrome?

    The effects of locked-in syndrome (LiS) on your body vary slightly depending on which type you have. People with locked-in syndrome are often initially thought to be in a comabefore recognition of consciousness. Most people with locked-in syndrome cannot consciously or voluntarily: 1. Chew. 2. Swallow. 3. Speak. 4. Make facial expressions. 5. Produ...

    Depending on which form of locked-in syndrome (LiS) you have, you may or may not be able to feel physical pain. If you have the total immobility form of LiS, you won’t be able to feel physical pain due to total paralysis of your body. If you have the incomplete form of LiS, you may be able to feel physical pain and other sensations in certain areas...

    Locked-in syndrome (LiS) is caused by damage to a specific part of your brainstem called the pons. The pons is a broad horseshoe-shaped mass of nerve fibers that connects the medulla oblongata (the lowest portion of your brainstem) with the cerebellum (a part of your brain that plays a vital role in virtually all physical movement, particularly coo...

  2. Jul 24, 2023 · Locked-in syndrome (LIS) is a complex medical condition presenting with quadriplegia, bulbar palsy, and whole-body sensory loss due to damage in the brain stem, most commonly the anterior pons. Cognition, vertical eye movement, blinking, and hearing are classically preserved in patients suffering from the condition. The diagnosis of the locked-in syndrome is often challenging due to its ...

    • Joe M Das, Kingsley Anosike, Ria Monica D. Asuncion
    • 2023/07/24
    • 2021
  3. Locked-in syndrome; Other names: Cerebromedullospinal disconnection, de-efferented state, pseudocoma, ventral pontine syndrome: Locked-in syndrome can be caused by a stroke at the level of the basilar artery denying blood to the pons, among other causes. Specialty: Neurology, Psychiatry

  4. Jul 29, 2021 · Locked-in syndrome (LIS) is a neurological disorder in which there is damage to the ventral pons and caudal midbrain. An ischemic cause, such as basilar artery occlusion, can often lead to LIS. LIS has three subtypes: classical, partial, and total. There is loss of motion in the four extremities in classical LIS, loss of horizontal gaze, and ...

    • Taras Halan, Juan Fernando Ortiz, Juan Fernando Ortiz, Dinesh Reddy, Abbas Altamimi, Abimbola O Ajib...
    • 10.7759/cureus.16727
    • 2021
    • Cureus. 2021 Jul; 13(7): e16727.
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  6. For example, locked-in syndrome due to transient ischemia or a small stroke in the vertebrobasilar artery distribution may resolve completely. When the cause (eg, Guillain-Barré syndrome) is partly reversible, recovery can occur over months but is seldom complete. Favorable prognostic features include . Early recovery of lateral eye movements

  7. Nov 14, 2022 · Locked-in syndrome is typically preceded by a loss of consciousness and subsequent. coma. lasting for days or weeks. The following symptoms are detected on regaining consciousness: Paralysis of voluntary muscles. Paralysis of all 4 limbs and torso ( quadriplegia) Caused by interruption of the bilateral.

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