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Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug.
May 1, 2024 · Many viral illnesses and medicines can cause a measles-like rash known as a morbilliform rash. Learn the causes, symptoms, and when to call a doctor.
Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...
The rash consists of macular lesions that are red and usually 2–10 mm in diameter but may be confluent in places. A morbilliform rash is a rose-red flat or slightly elevated (maculopapular) eruption, showing circular or elliptical lesions varying in diameter from 1 to 3 mm, with healthy-looking skin intervening. [citation needed]
Mar 13, 2019 · The onset of a morbilliform eruption (MDE; also known as exanthematous or maculopapular drug eruption) typically occurs within 7 to 10 days after the initiation of the culprit drug. Occasionally a 14-day window has been noted.
Mar 8, 2021 · Exanthematous drug eruption, also known as a morbilliform or maculopapular drug eruption, is the most common type of drug hypersensitivity reaction [1]. Diagnosis of exanthematous drug eruption should be suspected in a patient receiving drug treatment who presents with a new onset rash.
Morbilliform drug eruption occurs in 1% to 5% of first-time drug users and is characterized by a widespread, maculopapular, symmetrically distributed rash. The highest drug-specific incidence is reported among patients exposed to antibiotics (1%–8%), particularly beta-lactams.
Jun 14, 2024 · Synonyms for maculopapular rash include exanthematous eruption (exanthem) and morbilliform eruption. Definitions. The term maculopapular rash typically implies an acute and generalised eruption. Morphological terms. Macule: a flat, circumscribed skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch.
Jun 28, 2012 · Exanthematous drug eruptions (also called morbilliform or maculopapular drug eruptions) are the most common drug-induced eruptions. 2,7 They and the much rarer and more serious...
Mar 4, 2022 · Morbilliform eruptions inspire a broad and varied differential spanning across inflammatory and infectious categories. The goal of this article is to help the clinician develop an approach toward the pediatric patient with a morbilliform eruption in the emergency room or hospital setting.
