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- There are four major processes: transduction, transmission, modulation, and perception. Transduction refers to the processes by which tissue-damaging stimuli activate nerve endings. Transmission refers to the relay functions by which the message is carried from the site of tissue injury to the brain regions underlying perception.
www.ncbi.nlm.nih.gov › books › NBK219252The Anatomy and Physiology of Pain - Pain and Disability ...
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A nociceptor (from Latin nocere 'to harm or hurt'; lit. 'pain receptor') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain.
Thus there are two major ascending pathways for pain: a direct lateral spinothalamic pathway and an indirect medial spinoreticulothalamic pathway. It is thought that the lateral pathway from the spinal cord to the ventrocaudal thalamus and to the cortex is responsible primarily for sharp, well-localized pains that arise near the body surface.
- Marian Osterweis, Arthur Kleinman, David Mechanic
- 1987
- 1987
Jul 24, 2018 · Pain is a vast subject and affects so many regions of an individual’s body that we feel pain originating from numerous roots, including cancer, fibromyalgia, neuropathic pain, persistent post-surgical pain, arthritis, childhood and adolescent pain, headache and migraine, orofacial pain, visceral pain, musculoskeletal pain and pelvic pain.
- Mun Fei Yam, Yean Chun Loh, Chu Shan Tan, Siti Khadijah Adam, Nizar Abdul Manan, Rusliza Basir
- 10.3390/ijms19082164
- 2018
- Int J Mol Sci. 2018 Aug; 19(8): 2164.
Central Pain Pathways: The Spinothalamic Tract. The pathways that carry information about noxious stimuli to the brain, as might be expected for such an important and multifaceted system, are complex. The major pathways are summarized in Figure 10.3, which omits some of the less well understood subsidiary routes.
- Dale Purves, George J Augustine, David Fitzpatrick, Lawrence C Katz, Anthony-Samuel LaMantia, James ...
- 2001
- 2001
Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging.
Aug 1, 2014 · The pain pathways form a complex, dynamic, sensory, cognitive, and behavioral system that evolved to detect, integrate, and coordinate a protective response to incoming noxious stimuli that threatens tissue injury or organism survival. 1.
