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  1. Apr 15, 2024 · Paxlovid rebound, also known as COVID rebound, is a recurrence of COVID symptoms or a positive test result taken after having the disease and testing negative. Yale experts tell you what you need to know.

  2. Feb 20, 2024 · Does Paxlovid cause rebound symptoms? A CDC review of COVID rebound studies found “no consistent association between treatment and rebound.” Paxlovid does not directly cause symptoms to return; in fact, only about 1 in 5 people who take Paxlovid experience rebound , and many of those are asymptomatic.

  3. May 9, 2024 · How to know if you're experiencing Paxlovid rebound. If you've taken Paxlovid and have recovered but then feel symptoms like coughing, sore throat, headache, and sore muscles coming back, you may be experiencing a Paxlovid rebound. Rebound symptoms are almost always milder than your initial symptoms when you first had COVID-19.

  4. Nov 13, 2023 · A new study by Harvard Medical School researchers at Massachusetts General Hospital and Brigham and Women’s Hospital has found that one in five individuals taking nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19 had a positive test result and shed live potentially contagious virus following an ...

  5. Mar 25, 2024 · Like all antivirals, Paxlovid works best early in the course of an illness—in this case, within the first five days of symptom onset, says Jeffrey Topal, MD, a Yale Medicine infectious diseases specialist who is involved in determining COVID treatment protocols for Yale New Haven Hospital patients.

  6. Aug 8, 2022 · The CDC defines Paxlovid rebound as when a patient who, after receiving a full five-day course of treatment, either has a reemergence of COVID symptoms or tests positive after a previous,...

  7. Dec 13, 2022 · Updated. Dec. 13, 2022, 12:57 p.m. ET. Reports of “Paxlovid rebound” popped up in the spring of 2022, as some people who had taken the antiviral medication experienced a recurrence of Covid...

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