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  1. Mar 6, 2017 · Dana Sparks. March 6, 2017. Sickle cell anemia is an inherited form of anemia — a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout your body. Normally, your red blood cells are flexible and round, moving easily through your blood vessels.

  2. Nov 7, 2018 · Sickle cell disease (SCD) is a monogenic disorder that afflicts approximately 100,000 Americans and millions of people worldwide. It is characterized by hemolytic anemia, vaso-occlusive crises, relentless end-organ injury, and premature death.

  3. Mar 9, 2022 · Sickle cell anemia. Request an Appointment. Symptoms & causes. Diagnosis & treatment. Doctors & departments. Departments and specialties. Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota.

  4. Feb 25, 2020 · February 25, 2020. Learn about the symptoms, causes, treatment of this inherited blood disorder that, in the United States, is more common among African Americans. Sickle cell anemia is an inherited form of anemia — a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout your body.

  5. "Sickle cell disease is a genetic, inherited disorder. It's caused by a mutation in the gene that encodes for hemoglobin," says Dr. Ferdjallah. For a baby to be born with the disease, both parents must carry a sickle cell gene. The normally flexible red blood cells turn into rigid crescent shapes — sickle cells— that get stuck in blood vessels.

  6. Mayo Clinic "Sickle cell disease is a genetic, it’s an inherited disorder. It's caused by a mutation in the gene that encodes our hemoglobin." Mayo Clinic's Dr. Asmaa Ferdjallah (esmah fer-jallah) says the normally flexible red blood cells turn into rigid crescent shapes — sickle cells— that get stuck in blood vessels. And that can

  7. Aug 3, 2023 · Sickle cell disease affects the hemoglobin within your red blood cells. A genetic mutation causes abnormal hemoglobin to clump together, causing the red blood cells to turn sickle shaped. These sickle-shaped cells cause blockages in your blood flow, which can lead to anemia, pain, infections and severe complications.

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