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  1. May 26, 2022 · Researchers experimented with organ donation as far back as the 18th century, resulting in many failures along the way. By the mid-20th century, scientists were performing successful surgeries, and now transplants are considered routine medical treatments.

  2. The idea of replacing diseased or damaged body parts has been around for millennia. Envisioned were complex transplants such as the “successful” transplantation of an entire leg by the 3rd century sainted physicians Cosmos and Damien, which is depicted in several famous paintings (Zimmerman 1998).

    • Clyde F. Barker, Clyde F. Barker, James F. Markmann
    • 10.1101/cshperspect.a014977
    • 2013
    • 2013/04
    • Race to Transplant
    • Shumway’s First
    • Bringing The Donor to Stanford
    • ‘A Three-Ring Circus’
    • A Fight to Keep The Patient Alive
    • Refining The Work

    In the race to be the first to transplant the human heart — and a race it was — Shumway, a tall, lanky country boy from Michigan, was considered the leader of the pack. His decades-long research working with Richard Lower, MD, in dogs in the laboratory, ultimately led to what remains the standard surgical technique for heart transplantation. The re...

    It was a shock to the Stanford program. Everyone had expected Shumway to be the first. In fact, Shumway’s first human heart transplant would be the world’s fourth. On Dec. 6, 1967, in New York, the first pediatric heart transplant was performed. The infant’s heart stopped beating after seven hours. Barnard performed a second transplant on Jan. 2, 1...

    That afternoon, Stinson was sent to pick up Virginia White at El Camino Hospital in an ambulance and deliver her, with her heart still beating, to Stanford Hospital at 3:30 p.m. Shumway received a neurologist’s confirmation of brain death to proceed, and the surgery began. Two surgical teams were set up in two adjoining rooms on the second floor of...

    Downstairs, all hell broke loose. Fifty or so journalists had arrived even before surgery began, according to an article in Stanford Reportby Spyros Andreopoulos, director of the medical center’s news office at the time. He had converted two classrooms into an impromptu press room. “The tip actually came from a reporter from the San Jose Mercury Ne...

    During the next few weeks, Stinson, who later joined the School of Medicine faculty, led the fight to keep Kasperak alive. The first five nights post-surgery, Stinson remained sleepless by his patient’s side. Meanwhile, the Stanford press office issued daily bulletins on Kasperak’s condition. “The patient, Mike Kasperak, 54 years old, was reported ...

    “We just ignored it all,” says John Schroeder, MD, a professor of cardiovascular medicine who in 1968 was a member of the Shumway team as a cardiology resident. He helped write the grant proposals that kept Stanford’s research program alive following Kasperak’s transplant. Returning to the laboratory, the Stanford physician-scientists continued to ...

  3. In 1905, Alexis Carrel (1873–1944) and C C Guthrie (1880–1963) in New York City did the first heart transplantation in a dog. In 1906, Mathieu Jaboulay (1860–1913) in Lyon used kidneys from pigs and goats to attempt xenotransplantation in a human patient.

    • Thomas Schlich
    • 2011
  4. Mar 4, 2019 · Short history of organ transplantation. The earliest descriptions of OT can be found in ancient Greek, Rome, Chinese, and Indian mythology involving bone, skin, teeth, extremity, and heart transplantation [1, 2]. In the sixteenth century, Italian surgeon Gasparo Tagliacozzi used skin transplant for plastic reconstruction.

    • Dmitri Bezinover, Fuat Saner
    • 2019
  5. May 6, 2024 · History of medicine - Organ Transplantation: In 1967 surgery arrived at a climax that made the whole world aware of its medicosurgical responsibilities when South African surgeon Christiaan Barnard transplanted the first human heart.

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  7. Dec 11, 2017 · Week 50: Dec. 15, 1967. It was a medical breakthrough generations in the making. For as long as doctors had understood the crucial role of the heart, they had dreamed of using transplants...

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