Yahoo Web Search

Search results

1. • • The main lessons derived from this study highlight that benznidazole remains the standard of care, and that reduced doses and shorter treatment periods (ie, 2 weeks) could remain effective in achieving parasitological clearance that is sustained for at least 6 months.
     www.thelancet.com › journals › laninf

     New treatment regimens for Chagas disease: light at the end ...

2. People also ask

   Could a shorter benznidazole regimen help treat Chagas disease?

   • Adopting a shorter benznidazole regimen could have an important public health impact by reducing demands on health-care systems and facilitating patient adherence to treatment, helping to remove barriers to treatment access for Chagas disease. Contributors BB, FB, FT, JG, GB, IR, NS-W, and SS-E conceived and designed the study.

   New regimens of benznidazole monotherapy and in ... - The Lancet

   www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30844-6/fulltext

   See all results for this question

   What is the current treatment for Chagas disease – benznidazole or nifurtimox?

   • Electronic address: ssosa@dndi.org. Background: Current treatment for Chagas disease with the only available drugs, benznidazole or nifurtimox, has substantial limitations, including long treatment duration and safety and tolerability concerns.

   New regimens of benznidazole monotherapy and in combination with f…

   pubmed.ncbi.nlm.nih.gov/33836161/

   See all results for this question

   What are the treatment options for Chagas disease (Bendita)?

   • 1. Chronic Chagas heart disease management: from etiology to cardiomyopathy treatment. 2. Benznidazole and posaconazole in eliminating parasites in asymptomatic T cruzi carriers. 3. New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double blind, randomised trial.

   Shorter treatment in chronic Chagas disease: a new promise?

   www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00687-4/fulltext

   See all results for this question

   Does benznidazole treat Chagas disease cardiomyopathy?

   • A randomised trial showed that benznidazole had no effect on disease progression in patients with mild chronic Chagas disease cardiomyopathy. A meta-analysis of observational studies showed that benznidazole treatment had no effect on clinical progression of patients with chronic Chagas disease.

   Shorter treatment in chronic Chagas disease: a new promise?

   www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00687-4/fulltext

   See all results for this question

3. www.thelancet.com › journals › laninfShorter treatment in chronic Chagas disease: a new promise?

   www.thelancet.com › journals › laninf

   Jan 10, 2024 · In The Lancet Infectious Diseases, Pau Bosh-Nicolau and colleagues report the results of three different regimens of benznidazole in patients with chronic Chagas disease. 78 patients were randomly assigned to control treatment arm (300 mg of benznidazole daily for 60 days), 77 to low-dose treatment (150 mg of benznidazole for 60 days), and 79 to...

4. www.thelancet.com › journals › laninfNew treatment regimens for Chagas disease: light at the end ...

   www.thelancet.com › journals › laninf

   The main lessons derived from this study highlight that benznidazole remains the standard of care, and that reduced doses and shorter treatment periods (ie, 2 weeks) could remain effective in achieving parasitological clearance that is sustained for at least 6 months.

5. pubmed.ncbi.nlm.nih.gov › 33836161New regimens of benznidazole monotherapy and in ... - PubMed

   pubmed.ncbi.nlm.nih.gov › 33836161

   New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial. Lancet Infect Dis. 2021 Aug;21 (8):1129-1140. doi: 10.1016/S1473-3099 (20)30844-6. Epub 2021 Apr 6. Authors.

   • Author: Faustino Torrico, Joaquim Gascón, Fabiana Barreira, Bethania Blum, Igor C Almeida, Cristina Alonso-V...

   • Publish Year: 2021

6. www.ncbi.nlm.nih.gov › pmc › articlesA Rapid Review on the Efficacy and Safety of Pharmacological ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jul 12, 2021 · Benznidazole and Nifurtimox are the only currently available drugs for Chagas disease treatment and both have considerable pitfalls, including the long duration of treatment and low tolerability.

   • Author: Cody J Malone, Immaculate Nevis, Eduardo Fernández, Ana Sanchez
   • DOI: 10.3390/tropicalmed6030128

   • Publish Year: 2021
   • Publication: Trop Med Infect Dis. 2021 Sep; 6(3): 128.

7. pubmed.ncbi.nlm.nih.gov › 33043726Benznidazole for the treatment of Chagas disease - PubMed

   pubmed.ncbi.nlm.nih.gov › 33043726

   Alternative strategies such as shorter regimens, lower doses, and fixed doses are currently being evaluated to improve access and the safety profile of this treatment. Expert opinion: Benznidazole is likely to continue to be the drug of choice for Chagas disease in the coming years.

8. Videos

   • 

     5:36

     youtube.com

     Chagas Disease, Causes, Signs and Symptoms, Diagnosis and Treatment

     Mar 17, 2019

     89.4K Views

   • 

     1:23

     youtube.com

     Chagas: new study puts researchers closer to shortening the length of treatment

     Aug 31, 2021

     150 Views

   • 

     12:53

     youtube.com

     Chagas Disease | American Trypanosomiasis | Causes, Symptoms and Treatment

     Jun 24, 2018

     70.9K Views

   View all

9. www.ncbi.nlm.nih.gov › pmc › articlesUse of benznidazole to treat chronic Chagas disease: An ...

   www.ncbi.nlm.nih.gov › pmc › articles

   May 16, 2022 · Use of benznidazole to treat chronic Chagas disease: An updated systematic review with a meta-analysis - PMC. Journal List. PLoS Negl Trop Dis. v.16 (5); 2022 May. PMC9135346. As a library, NLM provides access to scientific literature.