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1. • ICP1

     • Vibrio cholerae, the causative agent of the diarrheal disease cholera, is antagonized by the lytic phage ICP1 in the aquatic environment and in human hosts.
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     Anti-phage islands force their target phage to directly ...

2. People also ask

   Are cholera cases positively correlated with the isolation of vibriophages?

   • It was discovered in the 1930s that cholera cases were positively correlated with the isolation of vibriophages in the aquatic environment 106. In modern times, a delayed positive concordance between a rise in the number of cholera cases and a subsequent rise of vibriophages in the environment has been described 107.

   Cholera transmission: the host, pathogen and bacteriophage ... - Nature

   www.nature.com/articles/nrmicro2204

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   What is Vibrio cholerae?

   • Vibrio cholerae is a facultative pathogen that has an environmental reservoir in aquatic ecosystems and a pathogenic phase in the human small intestine. It produces cholera toxin in the small intestine that results in massive secretory diarrhoea containing billions of vibrios per litre.

   Cholera transmission: the host, pathogen and bacteriophage ... - Nature

   www.nature.com/articles/nrmicro2204

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   Does Vibrio cholerae protect against colonization of the mucosa?

   • As Vibrio cholerae is non-invasive, it has been suggested that intestinal secretory immunoglobulin A (sIgA) protects against colonization of the mucosa. Approximately 8 days after the onset of cholera, there is a peak in circulating V. cholerae antigen-specific lymphocytes that express gut-homing chemokine-receptors (see the figure) 112.

   Cholera transmission: the host, pathogen and bacteriophage ... - Nature

   www.nature.com/articles/nrmicro2204

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3. journals.plos.org › plospathogens › articleTransmission of Vibrio cholerae Is Antagonized by Lytic Phage ...

   journals.plos.org › plospathogens › article

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   Oct 24, 2008 · Cholera outbreaks are proposed to propagate in explosive cycles powered by hyperinfectious Vibrio cholerae and quenched by lytic vibriophage. However, studies to elucidate how these factors affect transmission are lacking because the field experiments are almost intractable.

   • Author: Eric J. Nelson, Ashrafuzzaman Chowdhury, James Flynn, Stefan Schild, Lori Bourassa, Yue Shao, Regina...

   • Publish Year: 2008

4. www.nature.com › articles › s41467/018/04786-5Anti-phage islands force their target phage to directly ...

   www.nature.com › articles › s41467/018/04786-5

   Jun 14, 2018 · Vibrio cholerae, the causative agent of the diarrheal disease cholera, is antagonized by the lytic phage ICP1 in the aquatic environment and in human hosts.

   • Author: Amelia C. McKitterick, Kimberley D. Seed

   • Publish Year: 2018

5. www.nature.com › articles › nrmicro2204Cholera transmission: the host, pathogen and bacteriophage ...

   www.nature.com › articles › nrmicro2204

   Nelson, E. J. et al. Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. PLoS Pathog. 4, e1000187 (2008).

   • Author: EJ Nelson, JB Harris, Jr Jg Morris, SB Calderwood, A Camilli

   • Publish Year: 2009

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7. www.annualreviews.org › content › journalsBacteriophage ICP1: A Persistent Predator of Vibrio cholerae

   www.annualreviews.org › content › journals

   Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. PLOS Pathog 4: 10 e1000187

8. www.ncbi.nlm.nih.gov › pmc › articlesMechanisms of the evolutionary arms race between Vibrio ...

   www.ncbi.nlm.nih.gov › pmc › articles

   This review highlights recent findings on the evolutionary arms race between the causative agent of cholera Vibrio cholerae and virulent bacteriophages (phages) ICP1, ICP2, and ICP3 isolated from cholera patient stool samples.

   • Author: Minmin Yen, Andrew Camilli

   • Publish Year: 2017

9. www.academia.edu › 14283508Transmission of Vibrio cholerae Is Antagonized by Lytic Phage ...

   www.academia.edu › 14283508

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   Transmission of Vibrio cholerae Is Antagonized by Lytic Phage and Entry into the Aquatic Environment. Stefan Schild. 2008, PLoS Pathogens. See Full PDF.

10. dash.harvard.edu › handle › 1Transmission of Vibrio cholerae Is Antagonized by Lytic Phage ...

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    Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. PLoS Pathogens 4 (10): e1000187. Abstract. Cholera outbreaks are proposed to propagate in explosive cycles powered by hyperinfectious Vibrio cholerae and quenched by lytic vibriophage.