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  1. Using this tool, the risk of early-onset sepsis can be calculated in an infant born > 34 weeks gestation. The interactive calculator produces the probability of early onset sepsis per 1000 babies by entering values for the specified maternal risk factors along with the infant's clinical presentation.

    • Classification

      Clinical Exam Description; Clinical Illness: Persistent need...

    • References

      Puopolo KM, Draper D, Wi S, Newman TB, Zupancic J, Lieberman...

  2. Mar 1, 2021 · Based on whether the physician ordered antibiotics, the investigators estimated a treatment threshold of 20%, which is substantially higher than the KP EOS treatment threshold.

    • Sharla Rent, Holly Brine, Maria Fernanda de Almeida, Ruth Guinsburg, Ligia Rugolo, Fabio Mosca, Dani...
    • 2021
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  4. Using the CDC national incidence of early-onset sepsis of 0.5 per 1,000 live births, the calculator estimates this infant's early-onset sepsis risk to be 2.12 per 1,000 births.

  5. No vignette reached the 50% cutoff necessary to define a treatment threshold. Conclusion: The test threshold used by the KP calculator is the same as the threshold chosen by clinicians given a vignette and risk estimate. The KP treatment threshold is lower than that derived using all 3 methods.

  6. The KP treatment threshold is lower than that derived using all 3 methods. Introduction. Neonatal early-onset sepsis (EOS) is an infrequent event, occurring in 0.30.5 per 1000 newborns,...

    • Sharla Rent, Holly Brine, Maria Fernanda de Almeida, Ruth Guinsburg, Ligia Rugolo, Fabio Mosca, Dani...
    • 2021
  7. Dec 1, 2018 · The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last 2 decades, primarily because of the implementation of evidence-based intrapartum antimicrobial therapy. However, EOS remains a serious and potentially fatal illness. Laboratory tests alone are neither sensitive nor specific enough to guide EOS management decisions. Maternal and infant clinical ...

  8. Calculate EOS risk at birth, after clinical assessment, using Neonatal Sepsis Calculator & document in the infants EMR (Done by RN) Parameters needed for EOS score calculation. Incidence of EOS: 0.5/1000 live births(CDC) (may use site incidence if available) Gestational Age (weeks and days)