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1. www.ncbi.nlm.nih.gov › pmc › articlesUpdates in Late-Onset Sepsis: Risk Assessment, Therapy and...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 11, 2022 · Abstract. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality within the neonatal intensive care unit (NICU) and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

   • Neonatal Sepsis - StatPearls - NCBI Bookshelf

     Neonatal sepsis refers to an infection involving the...

   • Global incidence and mortality of neonatal sepsis: a ...

     In the last decade (2009–2018), the incidence was 3930 (95%...

2. publications.aap.org › neoreviews › articleUpdates in Late-Onset Sepsis: Risk Assessment, Therapy, and ...

   publications.aap.org › neoreviews › article

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   Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration. Preterm infants—born at ever-decreasing gestational ages—are at particularly high risk for life ...

3. People also ask

   Is early onset neonatal sepsis more common than late onset?

   • In the overall time frame, estimated incidence and mortality was higher in early-onset than late-onset neonatal sepsis cases. There was substantial between-study heterogeneity in all analyses. Studies were at moderate to high risk of bias. Neonatal sepsis is common and often fatal.

   Global incidence and mortality of neonatal sepsis: a systematic review

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8311109/

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   How has the epidemiology of neonatal sepsis changed over time?

   • The epidemiology of neonatal sepsis has been changing with time . The incidence of EOS has decreased since the 1990s due to the introduction of universal screening of group B streptococcus (GBS) in pregnant women and intrapartum antibiotic prophylaxis (IAP) . However, rates of LOS have remained relatively the same.

   Neonatal Sepsis - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK531478/

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   What causes late onset neonatal sepsis?

   • Late-onset neonatal sepsis is usually acquired from the environment ( see Neonatal Hospital-Acquired Infection). Staphylococci account for 30 to 60% of late-onset cases and are most frequently due to intravascular devices (particularly central vascular catheters).

   Neonatal Sepsis - Pediatrics - MSD Manual Professional Edition

   www.msdmanuals.com/professional/pediatrics/infections-in-neonates/neonatal-sepsis

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4. www.msdmanuals.com › neonatal-sepsisNeonatal Sepsis - Pediatrics - MSD Manual Professional Edition

   www.msdmanuals.com › neonatal-sepsis

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   Neonatal sepsis can be early onset (≤ 3 days of birth) or late onset (after 3 days). Early-onset sepsis usually results from organisms acquired intrapartum, and symptoms appear within 6 hours of birth. Late-onset sepsis is usually acquired from the environment and is more likely in preterm infants, particularly those with prolonged ...

5. www.nature.com › articles › s41390/021/01696-zDiagnosis of neonatal sepsis: the past, present and future

   www.nature.com › articles › s41390/021/01696-z

   Nov 2, 2021 · Neonatal sepsis is still a major cause of morbidity and mortality despite advances in neonatal medicine. 4 Incidence varies from 1 to 4 cases per 1000 live births in high-income countries, but as ...

6. adc.bmj.com › content › archdischildGlobal incidence and mortality of neonatal sepsis: a ...

   adc.bmj.com › content › archdischild

   Jan 22, 2021 · Random-effects estimator for neonatal sepsis incidence in the overall time frame was 2824 (95% CI 1892 to 4194) cases per 100 000 live births, of which an estimated 17.6% 9 (95% CI 10.3% to 28.6%) died. In the last decade (2009–2018), the incidence was 3930 (95% CI 1937 to 7812) per 100 000 live births based on four studies from LMICs. In the ...