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- Initial attempts at surgical anesthesia began many centuries ago, with the plants of antiquity. The mandragora, or mandrake, was used as a sedative and to induce pain relief for surgical procedures.
pubmed.ncbi.nlm.nih.gov › 22584550Special article: mandragora: anesthetic of the ancients - PubMed
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The mandragora, or mandrake, was used as a sedative and to induce pain relief for surgical procedures. It has been depicted in tablets and friezes since the 16th century before the common era (BCE) and used for its sedative effects by Hannibal (second century BCE) against his enemies.
In it, he described how wine made of mandrake, containing alkaloids atropine and scopolamine, could provide surgical anesthesia. Over time, a myth propagated that the plant would shriek when uprooted, instantly killing its remover, while bringing love and fertility to its consumer.
The mandragora, or mandrake, was used as a sedative and to induce pain relief for surgical procedures. It has been depicted in tablets and friezes since the 16th century before the common era (BCE) and used for its sedative effects by Hannibal (second century BCE) against his enemies.
- Elie J. Chidiac, Romeo N. Kaddoum, Samir F. Fuleihan
- 2012
Oct 26, 2018 · Mandragora or mandrake was often used in combination with other plants in a sedative potion. Its potent toxicity made it the subject of superstition and magical rituals, and the root was said to resemble a human figure.
Mandrake's use as a surgical anaesthetic was first described by the Greek physician Dioscorides around AD 60, and its use as a tincture known as mandragora, or in combination with other herbs such as opium, hemlock and henbane is described in documents from pre-Roman times onwards 4.
- Anthony John Carter
- 10.1258/jrsm.96.3.144
- 2003
- J R Soc Med. 2003 Mar; 96(3): 144-147.
The mandragora, or mandrake, was used as a sedative and to induce pain relief for surgical pro - cedures. It has been depicted in tablets and friezes since the 16th century before the common era (BCE) and used for its sedative effects by Hannibal (second century BCE) against his enemies. The Romans used the mandrake for surgery.
Jun 28, 2020 · Mandragora officinarum belongs to the family of Solanaceae and is traditionally known as an aphrodisiac and is closely associated with witchcraft.
