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Jul 21, 2020 · Co-cultivation. It is quite typical to find multiple species of Streptomyces in traditional medical preparations such as soil or moonmilk [ 50, 54, 64 ]. Now, it has been discovered that competition and collaboration between Streptomyces and other species can also awaken silent antibiotic-synthesis clusters [ 65 ].
- Gerry A. Quinn, Aiya M. Banat, Alyaa M. Abdelhameed, Ibrahim M. Banat
- 10.1099/jmm.0.001232
- 2020
- J Med Microbiol. 2020 Aug; 69(8): 1040-1048.
Streptomycin is an aminoglycoside. [3] It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. [3] Albert Schatz first isolated streptomycin in 1943 from Streptomyces griseus. [5] [6] It is on the World Health Organization's List of Essential Medicines. [7]
- 84% to 88% IM (est.) 0% by mouth
- Kidney
- C₂₁H₃₉N₇O₁₂
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streptomycin, antibiotic synthesized by the soil organism Streptomyces griseus. Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943. The drug acts by interfering with the ability of a microorganism to synthesize certain vital proteins. It was the first antimicrobial agent developed ...
- The Editors of Encyclopaedia Britannica
Jul 4, 2023 · Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria. This activity will discuss the indications, mechanism of action, and contraindications of using streptomycin ...
- Mitchell Waters, Prasanna Tadi
- 2023/07/04
Jul 5, 2017 · Another important milestone in the history of antibiotics was the discovery of streptomycin (6, Figure 1) from Actinomyces griseus (now Streptomyces griseus), the first aminoglycoside antibiotic ...
Apr 27, 2022 · Streptomycin has been referred to as the “wonder drug” due to the transformative effect it had on the prognosis of patients suffering from tuberculosis when it was first discovered. It spurred the discovery and invention of antibiotic drugs within the category know as aminoglycosides. Over the decades, it has saved the lives of millions ...
He called his discovery penicillin, and it is widely recognized as the first modern antibiotic. The theories of Ehrlich and Fleming informed the work of Selman Waksman, whose research on soil microbiology ultimately lead to the discovery of streptomycin, an antibiotic to treat tuberculosis. Waksman (nee Zolman Abraham Waksman) was born to ...
