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  1. Unstable Angina. Unstable angina is caused by transient formation and dissolution of a blood clot (thrombosis) within a coronary artery. The clots often form in response to plaque rupture in atherosclerotic coronary arteries; however, the clot may also form because diseased coronary artery endothelium (endothelial dysfunction) is unable to produce nitric oxide and prostacyclin that inhibit ...

  2. Feb 7, 2024 · Angina pectoris occurs when. Cardiac workload and resultant myocardial oxygen demand exceed the ability of coronary arteries to supply an adequate amount of oxygenated blood. Such imbalance between supply and demand can occur when the arteries are narrowed. Narrowing usually results from. Coronary artery atherosclerosis.

  3. Unstable angina results from acute obstruction of a coronary artery without myocardial infarction. Symptoms include chest discomfort with or without dyspnea, nausea, and diaphoresis. Diagnosis is by electrocardiography (ECG) and the presence or absence of biomarkers. Treatment is with antiplatelets, anticoagulants, nitrates, statins, and beta ...

  4. Mar 22, 2024 · Angina (an-JIE-nuh or AN-juh-nuh) is a type of chest pain caused by reduced blood flow to the heart. Angina is a symptom of coronary artery disease. Angina also is called angina pectoris. Angina is often described as squeezing, pressure, heaviness, tightness or pain in the chest. It may feel like a heavy weight lying on the chest.

  5. Unstable Angina. Unstable angina, one of several acute coronary syndromes, causes unexpected chest pain, and usually occurs while resting. The most common cause is reduced blood flow to the heart muscle because the coronary arteries are narrowed by fatty buildups ( atherosclerosis) that can rupture, causing injury to the coronary blood vessel.

  6. Dec 22, 2020 · Unstable angina is a type of chest pain that occurs when a person is resting. Learn more about its symptoms, causes, and treatment options here. ... This article will explore what unstable angina ...

  7. Unstable angina is a clinical syndrome characterized by increased rate and severity of angina pectoris attacks and, sometimes but not always, accompanied by ECG changes similar to those seen in coronary insufficiency. According to the present conception of the pathogenesis, ruptures at points of high-grade stenosis in the epicardial coronary ...

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