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  1. KEY POINTS Ampicillin-sulbactam (Unasyn) is the combination of aminopenicillin ampicillin plus beta-lactamase inhibitor sulbactam Has activity versus Gram negatives (not Pseudomonas), Gram positives (not MRSA) and anaerobes Sulbactam has activity against Acinetobacter Adding sulbactam to ampicillin expands coverage to include Bacteroides fragilis, MSSA, and more Gram negative coverage Can work ...

  2. May 1, 2024 · Ampicillin and sulbactam combination is used to treat bacterial infections in many different parts of the body. Ampicillin and sulbactam combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth.

  3. As a CRI. 3.75-8.3mg/kg/hr (extra-label use) Brand Name (s) Unasyn®. Background. Ampicillin sodium-sulbactam sodium is a bactericidal, time-dependent β-lactam antibiotic with improved activity against Gram-negative organisms when compared to penicillin. The addition of sulbactam improves activity against β-lactamase-producing bacteria, such ...

  4. Find patient medical information for ampicillin-sulbactam intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

  5. Apr 4, 2023 · To reduce the development of drug-resistant bacteria and maintain effectiveness of ampicillin and sulbactam for injection, USP and other antibacterial drugs, ampicillin and sulbactam for injection, USP should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.

  6. Oct 27, 2023 · You should not use this medicine if you are allergic to ampicillin or sulbactam, or if you have ever had. a severe allergic reaction to any type of penicillin or cephalosporin antibiotic; or. liver problems (hepatitis or jaundice) while using Unasyn. Tell your doctor if you have ever had: liver disease; mononucleosis (also called "mono ...

  7. Ampicillin is a bactericidal, time-dependent β-lactam antibiotic with improved activity against Gram-negative organisms when compared to penicillin, though with somewhat less activity against Gram-positive organisms. There is also some efficacy against anaerobes. Ampicillin distributes widely through the plasma, and can cross into the prostate ...

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