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  1. Yellow fever (YF) is a viral disease, endemic to tropical regions of Africa and the Americas. YF principally affects humans and nonhuman primates, and is transmitted via the bite of infected mosquitoes. The agent of YF, yellow fever virus (YFV), can cause devastating epidemics of potentially fatal, hemorrhagic disease.

  2. Keywords: yellow fever, vaccine, history, cell culture, Theiler At the close of the 19th century, yellow fever was a known and feared pestilence of the western hemisphere and the coastal regions of West Africa, for which no cause or effective treatment was known.

  3. May 27, 2021 · Yellow Fever and the Panama Canal. At the turn of the 20th Century, US researchers in Cuba made the historic discovery that mosquitoes spread yellow fever. The finding was not only a medical breakthrough; it would also make possible one of the world’s greatest feats of engineering. 27 May 2021.

  4. May 5, 2022 · Philip Schuyler's letters about yellow fever in the Alexander Hamilton Papers reveal a complicated and many-sided character responding to a dangerous and frightening moment in American history.

  5. Nov 11, 2007 · In 1951, Max Theiler of the Rockefeller Foundation received the Nobel Prize in Physiology or Medicine for his discovery of an effective vaccine against yellow fever—a discovery first reported in the JEM 70 years ago. This was the first, and so ...

  6. Jun 17, 2015 · The belief that West and Central Africans and their descendants in the New World enjoy an innate immunity or resistance to yellow fever persists in the writings of many historians. They offer three arguments that such a racial immunity actually exists: first, that a consensus on the matter prevailed among historical observers of the disease; second, that patterns of lethality during yellow ...

  7. Yellow fever broke out in Boston in 1693, Philadelphia in 1793 and Norfolk, Virginia in 1855, but the worst American outbreak of yellow fever occurred in the Mississippi River Valley in 1878. Over the course of spring and summer of 1878, this region recorded 120,000 cases of yellow fever and between 13,000 and 20,000 deaths from the disease.

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