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Mar 9, 2018 · Pharmacodynamics. Clarithromycin is a macrolide antibiotic whose spectrum of activity includes many gram-positive (Staphylococcus aureus, S. pneumoniae, and S. pyogenes) and gram-negative aerobic bacteria (Haemophilus influenzae, H. parainfluenzae, and Moraxella catarrhalis), many anaerobic bacteria, some mycobacteria, and some other organisms including Mycoplasma, Ureaplasma, Chlamydia ...
Aug 10, 2017 · Clarithromycin (kla rith" roe mye' sin) is a semisynthetic macrolide antibiotic used widely to treat mild-to-moderate bacterial infections caused by sensitive agents. Clarithromycin, like other macrolide antibiotics such such as eythromycin and azithromycin, is bacteriostatic against many gram positive bacteria including many strains of ...
Aug 6, 2021 · No differences were found in baseline characteristics of the enrolled patients divided into those with early and late start of clarithromycin (Table (Table1). 1). The primary endpoint was achieved in 91.7% of early starters (44 out of 48 patients; 95% CIs 80.4–96.7%) and in 81.4% (34 out of 42 patients; 95% CIs 66.7–90.0%) of late starters.
Aug 18, 2020 · Clarithromycin (CAM), a semisynthetic macrolide antibiotic, is a widely used antibacterial drug. ... The interactions of CAM with methyl-PSL and PSL were found to be ...
Jul 25, 2011 · Other investigations of clarithromycin have found that serum AUC 0–24 /MIC is the most accurate predictor of clarithromycin antimicrobial efficacy. 6,7 As mentioned previously, macrolides accumulate in the respiratory epithelial lining fluid where M. pneumoniae have a localized pathogenic effect. We measured clarithromycin concentrations in ...
Jan 1, 2022 · In this study, A2144G and A2143G mutations were found in H. pylori clarithromycin-resistant strains, based on the PCR-RFLP assay; among the 38 (69.1%) clarithromycin-resistant H. pylori strains included in our study, 23 (60.5%) of the isolates carried the A2144G mutation, 19 (50%) carried the A2143G mutation, and 9 (23.7%) carried the double ...
Oct 30, 2021 · The treatment success rate for azithromycin–beta-lactam after 10 to 14 days was 87.55% and that for clarithromycin–beta-lactam after 5 to 7 days of therapy was 75.42%. Streptococcus pneumoniae was commonly found in macrolide groups, with 130 and 80 isolates in the clarithromycin-based and azithromycin-based groups, respectively. The length ...
