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  1. Almost all cancers can spread to the bone, but cancers that often spread there include breast, lung, prostate, kidney, melanoma, ovarian, and thyroid . The spine is the most common site for bone metastases. Other common sites are the hip bone (pelvis), upper leg bone (femur), upper arm bone (humerus), ribs, and the skull.

  2. Dec 6, 2022 · Merkel cell carcinoma. Merkel cell carcinoma causes firm, shiny nodules that occur on or just beneath the skin and in hair follicles. Merkel cell carcinoma is most often found on the head, neck and trunk. Sebaceous gland carcinoma. This uncommon and aggressive cancer originates in the oil glands in the skin.

  3. Aug 11, 2023 · Symptoms of squamous cell carcinoma of the skin include: A firm bump on the skin, called a nodule. The nodule might be the same color as the skin, or it might look different. It can look pink, red, black or brown, depending on skin color. A flat sore with a scaly crust. A new sore or raised area on an old scar or sore.

  4. Jun 21, 2021 · Stage 0 (Melanoma in situ): The melanoma is only in the top layer of skin (the epidermis). Stage I: Low-risk primary melanoma with no evidence of spread. This stage is generally curable with surgery. Stage II: Features are present that indicate higher risk of recurrence, but there is no evidence of spread.

  5. Hoarseness. Loss of appetite. Unexplained weight loss. Shortness of breath. Feeling tired or weak. Infections such as bronchitis and pneumonia that don’t go away or keep coming back. New onset of wheezing. If lung cancer spreads to other parts of the body, it may cause: Bone pain (like pain in the back or hips)

  6. Sometimes when bones are damaged by advanced cancer, the bones release calcium into the blood. This is called hypercalcaemia and can cause various symptoms such as: tiredness. feeling sick (nausea) constipation. irritability. thirst. confusion. Find out about treatment for cancer that has spread to the bones.

  7. Nov 8, 2023 · Iressa (gefitinib): Dry, itchy, and flaky skin. Tarceva (erlotinib): Dry, itchy, flaky skin; acne-like rash on the face; severe reactions that may cause blistering and peeling skin. Vargatef (nintedanib): Tiny red or purple spots on the skin that may resemble a rash. Xalkori (crizotinib): Itchy rash.

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