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  1. Apr 30, 2024 · There are two forms of diclofenac - diclofenac sodium and diclofenac potassium. The main difference between the two is that diclofenac potassium is absorbed into the body more quickly than diclofenac sodium. A quick action is useful where immediate pain relief is required, and a prolonged action is more useful in reducing inflammation.

  2. Jan 19, 2023 · Diclofenac sodium delayed-release (DR) tablet: The typical dosage is 50 mg by mouth 2 or 3 times a day, or 75 mg twice a day. Diclofenac sodium extended-release (ER) tablet: The typical dosage is 100 mg by mouth once daily. Diclofenac 1.5% topical solution: The typical dosage is to apply 40 drops to each affected knee 4 times a day.

  3. Hypovolemia—Must be corrected first before using this medicine. Heart surgery (eg, coronary artery bypass graft [CABG] surgery)—Should not be used to relieve pain right before or after the surgery. Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

  4. Oct 2, 2020 · Diclofenac (Solaraze, Voltaren) topical gel is a prescription medication used to treat osteoarthritis pain and actinic keratoses. Learn about side effects, warnings, dosage, and more.

  5. Oct 3, 2022 · Diclofenac (Cambia, Cataflam) is a nonsteroidal anti-inflammatory drug (NSAID). It can interact with several other medications and alcohol. Common diclofenac interactions include aspirin, blood thinners, and methotrexate. The main risks with many interactions are stomach bleeding and kidney damage. Topical forms of diclofenac, like Voltaren gel ...

  6. avoid combo: combo may incr. risk of GI ulceration, perforation, bleeding (incl. life-threatening), thromboembolism, HTN, hyperkalemia, renal impairment, other adverse effects (additive effects, duplicate tx) diclofenac sodium (generic) Find medical information for diclofenac sodium on epocrates online, including its dosing, contraindications ...

  7. Mar 9, 2018 · Diclofenac has a total volume of distribution of 5-10 L or 0.1-0.2 L/kg. 7 The volume of the central compartment is 0.04 L/kg. 8 Diclofenac distributes to the synovial fluid reaching peak concentration 2-4h after administration. 7 There is limited crossing of the blood brain barrier and cerebrospinal fluid concentrations only reach 8.22% of ...

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