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  1. Disorders of the hypothalamus and pituitary gland. Occasionally, male infertility can be due to a decrease or absence in the production of two hormones essential for sperm production: follicle stimulating hormone (FSH) and luteinizing hormone (LH). For example, patients born with Kallmann syndrome have a deficiency in the pulsatile secretion of ...

  2. Aug 9, 2023 · Binding of Growth Hormone (GH): Growth hormone is a peptide hormone secreted by the anterior pituitary gland in response to signals from the hypothalamus. It circulates in the bloodstream and binds to its specific receptor, known as the growth hormone receptor (GHR), which is expressed on the surface of target cells.

  3. The hypothalamus and the pituitary gland are connected by a structure called the infundibulum, which contains vasculature and nerve axons. The pituitary gland is divided into two distinct structures with different embryonic origins. The posterior lobe houses the axon terminals of hypothalamic neurons.

  4. May 1, 2023 · Disorders of the hypothalamic-pituitary axis can manifest in various clinical syndromes. Acromegaly and Pituitary Gigantism. Both acromegaly and pituitary gigantism are rare disorders of growth, occurring in anywhere between 40 to 125 per million people, that occur due to persistent secretion of growth hormone from the pituitary gland.

  5. Front (anterior) lobe, which accounts for 80% of the pituitary gland's weight. Back (posterior) lobe. The lobes are connected to the hypothalamus by a stalk that contains blood vessels and nerve cell projections (nerve fibers, or axons). The hypothalamus controls the anterior lobe by releasing hormones through the connecting blood vessels.

  6. Jul 30, 2022 · The hypothalamus region lies inferior and anterior to the thalamus. It connects to the pituitary gland by the stalk-like infundibulum. The pituitary gland consists of an anterior and posterior lobe, with each lobe secreting different hormones in response to signals from the hypothalamus. Table 1. Pituitary Hormones.

  7. Jan 16, 2024 · Hypothalamus and pituitary gland. ... Hypothalamus dysfunction can lead to absent or delayed puberty and no sense of smell, as in Kallman syndrome. This is a genetic condition that causes problems ...

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