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Mar 16, 2006 · Rapid immunoperoxidase demonstration of Rickettsia rickettsii in fixed cutaneous specimens from patients with Rocky Mountain spotted fever. Am J Clin Pathol 1990;93:410--4. Walker DH, Cain BG, Olmstead PM. Laboratory diagnosis of Rocky Mountain spotted fever by immunofluorescent demonstration of Rickettsia rickettsii in cutaneous lesions. Am J ...
The extent to which other SFG Rickettsia are pathogenic in dogs is unclear; however, SFG Rickettsia seroprevalence is high among dogs in the United States and Mexico (3,4). The increased R. rickettsii seroprevalence in humans in the United States during the past decade has been attributed to SFG Rickettsia cross-reactivity (1,5).
Four ticks (Figure 1) (7%) had DNA evidence of genera-wide Rickettsia species; however, none of the ticks yielded positive PCR results in the R. rickettsii-specific assay. Among stray dogs, six dogs sampled at one of the study sites were identified to be free-roaming dogs from American Indian tribal lands not known to be impacted by RMSF; all ...
Detection of antibodies to Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, by indirect fluorescent antibody test. Performed at 1:64, 1:128, 1:256, 1:512, 1:1024, and 1:2048 dilutions. Collect serum from clotted blood in a non-additive tube (e.g. plain red top or serum separator). When possible, transfer clear serum ...
Mar 23, 2021 · Background. Rocky Mountain spotted fever (RMSF) is a tick-borne disease caused by the organism Rickettsia rickettsii. Although RMSF can be lethal, it is curable. RMSF is the most common rickettsial infection. The organism is endemic in parts of North, Central, and South America, especially in the southeastern and south-central United States.
May 10, 2012 · We examined the potential role of domestic dogs in transmission of SFG Rickettsia. R. rickettsii, the causative agent of Rocky Mountain spotted fever, is known to cause clinical disease in dogs, and it is associated with signs and symptoms that are similar to human disease, including cutaneous petechiae and ecchymoses, anorexia, depression ...
Sep 1, 2023 · As a reservoir, dogs are one of the pivotal points in the ecology of R. rickettsii. Methods to disrupt the cycle of R. rickettsii transmission to humans are des-perately needed. An effective canine vaccine that reduces or prevents the acquisition of R. rickettsii from Rh. sanguineus would be one of the most efficient approaches to break the ...
