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  1. Sepsis is the life-threatening condition that arises when the body's response to an infection damages its own tissues and organs. It can lead to shock, failure of multiple organs, and death. Organ failure and death are more likely if sepsis is not recognized early and not treated promptly. Sepsis is….

  2. en.wikipedia.org › wiki › SepsisSepsis - Wikipedia

    Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]

  3. Jun 30, 2016 · Since 1991, the consensus definition of sepsis has been the ‘systemic inflammatory response (SIRS) to a microbial infection’ (Refs 2,3) , with SIRS defined as at least two of the following ...

  4. Sepsis is a clinical syndrome defined by a systemic response to infection. With progression to sepsis-associated organ failure (ie, severe sepsis) or hypotension (ie, septic shock) mortality increases. Sepsis is a cause of considerable mortality, morbidity, cost, and health care utilization. Abnormalities in the inflammation, immune, coagulation, oxygen delivery, and utilization pathways play ...

  5. Jan 30, 2024 · Sepsis is the most common serious complication of infection. It affects people worldwide, but has a particularly high burden in low- and middle-income countries where resources to treat it are more limited. Estimates from 2017 suggest 48.9 million cases of sepsis occur each year, with 11 million deaths. Many patients who survive sepsis suffer long-term complications as a result.1Treatment for ...

  6. Sepsis is a life-threatening condition that arises when the body’s response to an infection injures its own tissues and organs. It occurs when the body’s immune system – which normally helps to protect us and fight infection – goes into overdrive. It can lead to shock, multiple organ failure and sometimes death, especially if not ...

  7. Sepsis is a life-threatening organ dysfunction caused by an unregulated response of a host. Septic shock is its most severe form. It is manifested by a drop in blood pressure, which decreases tissue perfusion pressure, causing hypoxia that is characteristic of shock. Sepsis is still one of the leading causes of mortality worldwide.

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