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  1. Background The incidence of Early Onset Neonatal Sepsis (EONS) in the UK is currently estimated at 0.9/1000 live births. NICE have published guidance (CG149) for treating infants based on antenatal risk factors and clinical indicators. In the UK, 13–20% of infants are treated for suspected EONS based on CG149. This represents a significant burden, impacting on family bonding, breastfeeding ...

  2. The Kaiser Permanente sepsis risk calculator (SRC) has safely and dramatically reduced investigations and antibiotics for suspected EOS in the USA. This study evaluates the current management of suspected EOS against the NICE guideline CG149 and the SRC.

  3. Jan 1, 2024 · The Kaiser Permanente neonatal early-onset sepsis (EOS) calculator is an evidence-based sepsis risk assessment tool that has demonstrated potential to reduce antibiotic usage in this population. The incidence of early-onset sepsis in most HICs is 0.4–0.8 per 1000 live births.

  4. Jun 9, 2014 · The sepsis calculator is just one example of how big data is helping to improve the quality of care for Kaiser Permanente’s smallest members. Every year, the Northern California Region provides care for 35,000 newborns and 350 very low birth weight infants under 1,500 grams (3 pounds, 5 ounces).

  5. The Kaiser Permanente Perinatal Research Unit developed an online risk prediction web-based tool that has led to drastic reductions in empiric antibiotic administration: the neonatal early-onset sepsis calculator.1 Use of the tool has been adopted quickly by many neonatal clinics worldwide, both in clinical and research contexts. However, the current international reliance on the Kaiser ...

  6. Feb 23, 2022 · Research has now shown that use of the Kaiser Permanente neonatal sepsis calculator can reduce antibiotic use and unnecessary sepsis evaluation. Design/Methods: We collected baseline data from 2018 by chart review from neonates >/= 35 weeks gestational age at birth that were inborn and admitted to the NICU.

  7. Aug 24, 2022 · Kaiser Permanente sepsis risk scores in neonates receiving parenteral antibiotics within 72 h of birth according to CG149-NICE criteria for early-onset neonatal sepsis, and meeting Kaiser Permanente criteria for normal care, enhanced observations, and parenteral antibiotics