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Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
Mar 31, 2022 · Sepsis is a systemic infection caused by pathogens invading the blood circulation, growing, and reproducing in it, and producing toxins leading to serious health conditions and neonatal death. The incidence rate is about 0.1-1% of live birth infants, which accounts for 16.4% of very low birth weight (VLBW) infants.
May 4, 2020 · This cohort study of 217 480 infants identified 235 cases of early-onset sepsis from 2015 to 2017; Escherichia coli (86 [36.6%]) and group B streptococcus (71 [30.2%]) were the most common pathogens, with E coli most frequent among preterm infants and group B streptococcus most frequent among term infants.
Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1]. Neonatal sepsis is divided into two groups based on the time of presentation after birth: early-onset sepsis (EOS ...
Jul 19, 2022 · We demonstrated the spatial distribution using choropleth maps. Results: During 2016-2020, 95,983 neonatal sepsis cases were reported and of these, 71,262 (74.2%) were EOS. Overall incidence of neonatal sepsis was 17.4/1,000 live-births. Nationally, incidence of sepsis was generally highest at the Regional Referral Hospital (RRH) level (68/1000 ...
Aug 2, 2018 · Sepsis is the commonest cause of neonatal mortality and is probably responsible for 30-50% of the total neonatal deaths each year in developing countries . According to the current united nation estimate, the neonatal death reduced by 48% from the 1990 estimate to 28 per 1000 live births in 2013 while the reduction rate of under-five mortality ...
Aug 20, 2020 · Neonatal sepsis is divided into early-onset (defined as the onset of sepsis in the first three days of life) and late-onset (after day three of life) sepsis. 1 Early-onset sepsis (EOS) is associated with prematurity, a low birth weight, and obstetric complications, such as premature rupture of membranes (PROM), and chorioamnionitis, 7–10 and the major gram-negative pathogen causing EOS is ...
