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Time-kill experiments were performed with clarithromycin, azithromycin, 14-hydroxy-clarithromycin, and a combination of clarithromycin and 14-hydroxy-clarithromycin at the following concentrations found in lung ELF: clarithromycin, 30 μg/ml; azithromycin, 3 μg/ml; and 14-hydroxy-clarithromycin, 2 μg/ml (3, 7, 19, 24, 27).
May 2, 2014 · The renal clearance of clarithromycin is, however, relatively independent of the dose size and approximates the normal glomerular filtration rate. The major metabolite found in urine is 14-OH clarithromycin, which accounts for an additional 10% to 15% of the dose with either a 250 mg or a 500 mg tablet administered every 12 hours.
Feb 1, 2020 · Macrolides are a class of drugs used to manage and treat various bacterial infections. Azithromycin, clarithromycin, and erythromycin are commonly used to treat infections like pneumonia, sinusitis, pharyngitis, and tonsillitis. They are also used in uncomplicated skin infections and otitis media in pediatric patients. Clarithromycin is used to treat Helicobacter pylori infections in standard ...
Jan 15, 2023 · Azithromycin is an antimicrobial medication used to treat and manage bacterial infections, including community-acquired pneumonia and sexually transmitted diseases. It is in the macrolide class of antimicrobials. The disorders treated by azithromycin are important causes of infectious disease morbidity and mortality in the United States. This activity reviews the indications, contraindications ...
Dec 5, 2023 · The renal clearance of clarithromycin is, however, relatively independent of the dose size and approximates the normal glomerular filtration rate. The major metabolite found in urine is 14-OH clarithromycin, which accounts for an additional 10% to 15% of the dose with either a 250 mg or a 500 mg tablet administered every 12 hours.
Clarithromycin. Brand names: Klaricid, Klaricid XL, Xetinin XL. Find out how clarithromycin treats chest infections and pneumonia, and how to take it. NHS medicines information on clarithromycin – what it's used for, side effects, dosage and who can take it.
Sep 24, 2022 · Overall, the quality of available data on the safety of maternal use of erythromycin, clarithromycin, and azithromycin in early pregnancy was found to be low. Moreover, the available evidence was considered to be insufficient to establish the absence of a small increased risk of major malformations or cardiovascular malformations following ...
