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Mar 5, 2024 · SYNM. synemin. Gene ID: 23336, updated on 5-Mar-2024. Gene type: protein coding. Also known as: DMN; SYN. See all available tests in GTR for this gene. Go to complete Gene record for SYNM. Go to Variation Viewer for SYNM variants.
Dec 1, 2019 · Myocardin (MYOCD) is a critical regulator of smooth muscle cell (SMC) differentiation, but its transcriptional targets remain to be exhaustively characterized, especially at the protein level. Here we leveraged human RNA and protein expression data to identify novel potential MYOCD targets. Using co …
Feb 8, 2024 · synemin gene encodes proteins belonging to the intermediate filament which confer resistance to mechanical stress and modulate cell shape. Dmn is expressed in reactive astrocytes in neurotrauma and interacts differentially with Vim and Gfap. Enables intermediate filament binding activity. Acts upstream of or within fast-twitch skeletal muscle ...
View mouse Synm Chr7:67379909-67409490 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
此蛋白已被发现，以形成结蛋白之间的联系，这是IF网络的一个亚基，以及细胞外基质，并且提供了在肌肉的重要结构支撑。. 两个编码不同同种型的可变剪接变体已被用于这个基因说明。. [由RefSeq的，2008年7月提供] OMIM数据库中对SYNM基因的介绍 Wikipedia数据库中 ...
Jun 14, 2010 · Synemin (SYNM) is a type IV intermediate filament that has recently been shown to interact with the LIM domain protein zyxin, thereby possibly modulating cell adhesion and cell motility. Owing to ...
Function. Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteromeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteromeric IFs to adherens ...
