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Mar 31, 2023 · Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). Consequently, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis.
Mar 31, 2023 · Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). Consequently, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis.
Mar 18, 2017 · Practice Essentials. Factor XIII (FXIII), which was initially termed fibrin stabilizing factor, is involved in clot preservation. FXIII also participates in other physiologic processes, including wound repair and healing. FXIII deficiency, an autosomal recessive disorder, is a rare but potentially life-threatening cause of a hemorrhagic diathesis.
Mar 31, 2023 · Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). Consequently, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis.
Mar 31, 2023 · Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). Consequently, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis.
Recheck platelet count in a citrate tube. If the platelet count falls within the reference range in the citrate tube, pseudothrombocytopenia is diagnosed. If clumping occurs in citrate tube as well, it may indicate type 2B von Willebrand disease, in which abnormal von Willebrand factor spontaneously binds to and aggregates platelets.
Delbruck C, Miesbach W. The Course of von Willebrand Factor and Factor VIII Activity in Patients with von Willebrand Disease during Pregnancy. Acta Haematol. 2019. 142 (2):71-8. [QxMD MEDLINE Link]. . [Guideline] James PD, Connell NT, Ameer B, et al. ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease.
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related to: von willebrand in pregnancy causes site:medscape.comSee official information about a von Willebrand disease treatment for adults.
