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Aug 14, 2019 · The dorsal raphe nucleus (DRN) is a major source of neuromodulators in the central nervous system, and is the largest of the serotonergic nuclei, containing approximately a third of all serotonergic neurons (5-HT neurons) in the brain ( Hornung, 2010 ). DRN 5-HT neurons send highly divergent projections that target many functionally distinct ...
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Raphe nuclei. The Raphe nuclei (singular = Raphe nucleus) are a cluster of nuclei in the hindbrain which release a neurotransmitter called serotonin (5-HT). The serotonin molecules get sent all over the brain, where they are needed for all sorts of roles. [1] '. Selective serotonin reuptake inhibitor' (SSRI) antidepressants are believed to act ...