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Dec 5, 2019 · The ventral tegmental area (VTA) is a hub of the mesocorticolimbic circuitry that plays a significant role in reward, motivation, cognition, and aversion. Dopaminergic (DA) neurons, which make up 65% of neurons in the VTA, have been the primary focus of research into this brain region.
May 1, 2019 · The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are assumed to play a key role in dopamine-related functions such as reward-related behaviour, motivation, addiction and motor functioning. Although dopamine-producing midbrain structures are bordering, they show significant differences in structure and function that ...
Fig. 3. Reward and stress activate VTA dopamine neurons, increasing extracellular dopamine in the mPFC and NAcSh. Both rewarding and stressful stimuli induce dopaminergic increases in ventral tegmental area (VTA) projection targets, namely, the medial prefrontal cortex (mPFC) and nucleus accumbens shell (NAcSh), to a similar degree.
The VTA/NAcc reward circuit. Ventral tegmental area (VTA) contains cell bodies of dopaminergic neurons projecting to the nucleus accumbens, amygdala, hippocampus, and prefrontal cortex. Defined as the mesocorticolimbic dopamine system (Albanese and Minciacchi, 1983 ), these neurons are critically implicated in brain mechanisms of reward ...
Oct 5, 2016 · The ventral tegmental area, or VTA, is one of the two largest dopaminergic regions of the brain (the other being the substantia nigra). Dopamine neurons leav...
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The ventral tegmental area is part of what is known as the brain’s reward circuit, which, coincidentally, was discovered by Olds’s father, James, when she was 7 years old. This circuit is considered to be a primitive neural network, meaning it is evolutionarily old; it links with the nucleus accumbens.
Feb 12, 2021 · The ventral tegmental area (VTA) is a subcortical structure that plays a pivotal role in reward processing, learning and memory. Despite the significant interest in this nucleus in cognitive neuroscience, there are currently no available, anatomically precise VTA atlases derived from 7 T MRI data that cover the full region of the VTA.
