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James W. Gray, Birmingham Children's Hospital, Department of Microbiology, Steelhouse Lane, Birmingham, B46NH, UK. jim.gray@bch.nhs.uk Financial & competing interests disclosure: The author has no ...
Jan 16, 2024 · Background Late-onset neonatal sepsis (LOS) is common in preterm neonates, with increasing incidence in recent years. In the present study, we examined the epidemiology, clinical presentation, and complications of LOS in Cyprus and quantified possible risk factors for the development of this condition. Methods The study subjects were preterm neonates admitted in the Neonatal Intensive Care ...
Pediatr Health. 2008;2(4):477-484. An understanding of risk factors for LOS can also identify the high-risk aspects of neonatal care that should be the target of infection prevention interventions ...
Abstract. Late-onset sepsis in premature infants is a major cause of morbidity, mortality, and increased medical costs. Risk factors include low birth weight, low gestational age, previous antimicrobial exposure, poor hand hygiene, and central venous catheters. Methods studied to prevent late-onset sepsis include early feedings, immune globulin ...
Dec 1, 2005 · A simple prediction-scoring model for LNS defined as culture-proven sepsis occurring 72 hours after birth was developed and validation of the scores suggested good diagnostic performance. OBJECTIVE:Insufficient tools for bedside prediction of late-onset neonatal sepsis (LNS) initiated this study. The objective was to develop and validate a simple prediction-scoring model for LNS defined as ...
Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration. Preterm infants—born at ever-decreasing gestational ages—are at particularly high risk for life ...
Sep 19, 2023 · There are approximately 1.3 million cases of neonatal sepsis reported worldwide with deaths occurring more commonly in preterm and low-weight newborns. Neonatal sepsis is the third major cause of neonatal deaths resulting in 203,000 deaths per year. It is divided into two subtypes based on time of occurrence: early-onset neonatal sepsis (ENS ...
