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Jun 4, 2024 · Introduction. Erick von Willebrand described in 1925 the disease that would later bear his name. Von Willebrand’s disease (VWD) is a disorder of von Willebrand factor (VWF), which is a glycoprotein that contributes to platelet adhesion to the endothelium and is a carrier protein for plasma factor VIII [].
Jun 11, 2024 · As a result, if older people with borderline von Willebrand factor levels around 50 IU/dL have a bleeding history, Atiq tells HemAware that “they should be managed similarly to patients with von Willebrand factor levels between 30–50 IU/dL, considering potential changes in von Willebrand factor levels that could have occurred with age ...
6 days ago · von Willebrand Factor (VWF) is well recognized for being dysregulated in various malignancies and has emerged as a potential biomarker for cancer detection. The present meta‑analysis aimed to elucidate the association between plasma VWF and the incidence and metastasis of cancer. For this purpose, a comprehensive search was conducted across multiple databases from their inception until March ...
6 days ago · VGA039 has potential to be a universal hemostatic therapy that can treat numerous bleeding disorders, including von Willebrand disease. As a subcutaneously self-administered antibody therapy with convenient dosing, VGA039 has the potential to significantly reduce treatment burden for patients. About von Willebrand disease
Jun 19, 2024 · Managing Severe Cases: Focus on Type 3 Von Willebrand Disease. Type 3 VWD is the most severe form, characterized by a near-total absence of von Willebrand factor and FVIII, leading to significant and potentially life-threatening bleeding episodes. Management may involve regular prophylactic treatment with VWF concentrates to prevent bleeding.
Jun 18, 2024 · Educational Impact Challenge. The goal of this activity is to discuss the management of patients with von Willebrand Disease (vWD) and examine the emerging role of prophylaxis in the management of vWD. Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Page 1 of 4.
6 days ago · Von Willebrand disease (VWD) is a bleeding disorder in which the blood does not clot properly. In VWD, defective or low amounts of von Willebrand factor (VWF) lead to insufficient platelet adhesion and unstable clot formation. VWD causes severe bleeding that can damage organs and lead to significant impact on patients’ daily lives.
