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Filoviridae (/ ˌ f aɪ l oʊ ˈ v ɪr ɪ d iː /) is a family of single-stranded negative-sense RNA viruses in the order Mononegavirales. Two members of the family that are commonly known are Ebola virus and Marburg virus.
Mar 27, 2023 · Filoviruses, viral family Filoviridae, can cause hemorrhagic fever in humans and primates. There are three known genera of filoviruses: Cuevavirus, Marburgvirus, and Ebolavirus. These further subdivide into six species: Zaire, Sudan, Tai Forest, Bundibugyo, Reston, and Bombali.
Filoviridae is a family for negative-sense RNA viruses with genomes of about 13.1–20.9 kb that infect fish, mammals, and reptiles (Table 1.Filoviridae).
The Filoviridae consists of 2 genera: Ebolavirus (consisting of 5 species) and Marburgvirus (consisting of 2 species). The specific vectors of these viruses have not been confirmed, but fruit bats are the prime candidates; thus, Filoviridae are not arboviruses.
Filoviruses are filamentous, enveloped particles with a negative-sense, single-stranded RNA genome, approximately 19 kb long. Genes are defined by conserved transcriptional start and termination signals and arranged linearly. A single glycoprotein forms the spikes on the virion surface.
filovirus, any virus belonging to the family Filoviridae. Filoviruses have enveloped virions (virus particles) appearing as variably elongated filaments that are about 80 nm (1 nm = 10 −9 metre) in diameter and generally between 650 and 1,400 nm in length.
Apr 25, 2019 · Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15–19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and are highly virulent.
The Filoviridae are a family of negative-strand RNA viruses that include several important human pathogens. Ebola virus (EBOV) and Marburg virus are well-known filoviruses which cause life-threatening viral hemorrhagic fever in human and nonhuman primates.
Oct 6, 2015 · Filovirus disease is characterized by uncontrolled virus replication and the activation of host responses that contribute to pathogenesis. Underlying these phenomena is the potent suppression of...
Jan 1, 2018 · The Filoviridae are a family of negative-strand RNA viruses that include several important human pathogens. Ebola virus (EBOV) and Marburg virus are well-known filoviruses which cause life-threatening viral hemorrhagic fever in human and nonhuman primates.
