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May 20, 2024 · Our results show significant genetic diversity among dengue virus variants that circulated on the island over the past decade. This diversity indicates the simultaneous presence of multiple lineages and closely related viruses, which may have resulted from regular introductions of new variants.
3 days ago · Dengue virus (DENV) poses a significant threat to global health, infecting approximately 390 million people annually. This virus comprises four serotypes capable of causing severe disease. Genetic analyses are crucial for understanding the epidemiology, evolution, and spread of DENV. Although previous studies have focused on the envelope protein-coding (E) gene, only a few primers can ...
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May 14, 2024 · About 1 in 4 dengue virus infections are symptomatic. Approximately 1 in 20 patients with dengue progress to develop severe, life-threatening disease called severe dengue. Because there are four dengue viruses, people can be infected with DENV multiple times in their life.
May 4, 2024 · Dengue virus (DENV) is a continuing global threat that puts half of the world’s population at risk for infection. This mosquito-transmitted virus is endemic in over 100 countries. When a mosquito takes a bloodmeal, virus is deposited into the epidermal and dermal layers of human skin, infecting a variety of permissive cells, including keratinocytes, Langerhans cells, macrophages, dermal ...
May 14, 2024 · Nucleic Acid Amplification Test (NAAT) What the test is. A NAAT is a generic term referring to molecular tests used to detect viral genomic material (Nucleic Acids). NAATs are a preferred method of diagnosis because they can provide confirmed evidence of infection. How and when NAAT should be used during infection.
3 days ago · Evolution remains an incessant process in viruses, allowing them to elude the host immune response and induce severe diseases, impacting the diagnostic and vaccine effectiveness. Emerging and re-emerging diseases are among the significant public health concerns globally. The revival of dengue is mainly due to the potential for naturally arising mutations to induce genotypic alterations in ...
3 days ago · This database contains a mixture of case definitions with only Dengue Haemorrhagic Fever (DHF) reported 2000–2008, combined dengue and DHF 1995–1999 and 2009–2015, and combined non-severe ...
