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Jan 21, 2022 · The SAPHO syndrome was given its acronymic name based upon the presence of synovitis, acne, pustulosis, hyperostosis, and osteitis in the patients described in early reports. It is a rare inflammatory disorder of bone, joints, and skin, which was first described as a syndrome in 1987 .
SAPHO syndrome involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters containing pus) often on the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bones).
SAPHO syndrome includes a variety of inflammatory bone disorders that may be associated with skin changes. These diseases share some clinical, radiologic, and pathologic characteristics. An entity initially known as chronic recurrent multifocal osteomyelitis was first described in 1972.
SAPHO syndrome is suspected when a patient presents with a pustular skin disease in association with rheumatic pain. Magnetic resonance imaging ( MRI scan) shows inflammation of the bone marrow or joints at characteristic sites such as the collar bone, breast bone, pelvis, heel, and lower jaw.
Mar 2, 2020 · SAPHO syndrome is a rare disorder with a wide range of possible symptoms. Some common symptoms include blisters, acne, and inflammation of the joints and bones.
Sappho ( / ˈsæfoʊ /; Greek: Σαπφώ Sapphṓ [sap.pʰɔ̌ː]; Aeolic Greek Ψάπφω Psápphō; c. 630 – c. 570 BC) was an Archaic Greek poet from Eresos or Mytilene on the island of Lesbos. [a] Sappho is known for her lyric poetry, written to be sung while accompanied by music.
May 21, 2024 · The SAPHO syndrome is an acronym that refers to a rare syndrome that is manifested by a combined occurrence of 2: S: synovitis. A: acne. P: pustulosis. H: hyperostosis. O: osteitis. Epidemiology. SAPHO classically tends to present in young to middle-aged adults. Presentation in the pediatric population is not uncommon.
