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  1. Feb 21, 2024 · When you have liver disease already, an AFP of more than 200 ng/mL usually means you have liver cancer. AFP-L3% Test. For people who have a raised AFP but less than 200 ng/mL, the doctor may...

  2. Jun 7, 2023 · Alpha-fetoprotein (AFP) is a tumor marker used to detect and diagnose certain cancers and liver diseases. AFP blood testing may also be performed during pregnancy to determine a baby's risk for a congenital disability or genetic disorder.

  3. Jun 15, 2023 · Doctors often monitor tumor markers in the blood to help diagnose and treat liver cancer. Alpha-fetoprotein (AFP) is the most common tumor marker that doctors monitor.

  4. Aug 23, 2022 · A very high level of AFP or a sudden increase can be an early sign of liver cancer. Most medical experts don't recommend measuring AFP levels to screen for cancer in these diseases. But, some health care providers may still use an AFP tumor marker test with other tests to watch for liver cancer.

  5. Oct 17, 2022 · Healthcare providers may also use AFP tumor marker tests to plan cancer treatment. For example, if you have high AFP levels and liver cancer, targeting cancer cells with specific drugs (targeted therapy) may be an effective treatment.

  6. May 13, 2013 · AFP mRNA is considered the most valuable marker for circulating HCC cells and is only present in active HCC cells. If other interferences such as genital tumors and peripheral blood are excluded, AFP mRNA could be used as a significant marker for spreading of HCC in blood. In advanced liver cancer, the rate of AFP mRNA expression reaches 100%.

  7. You may need this test if your healthcare provider thinks you may have liver cancer, testicular cancer, or cancers of the brain, mediastinum (chest), or blood. This test is also used to track cancer treatment, or see if cancer has come back after treatment.

  8. Jan 1, 2022 · During fetal and neonatal life, alpha-fetoprotein (AFP) is produced by yolk sac, fetal liver and gastrointestinal tract. Only a trace amount of AFP can be measured in adults due to its rapid decline in adults[1-4]. The use of AFP as a tumor marker for hepatocellular carcinoma (HCC) was first proposed in 1960s.

  9. May 15, 2024 · Alpha-fetoprotein (AFP) is the most widely used tumor marker for detecting liver cancer. However, other cancers and certain conditions, including pregnancy, hepatitis, and other types of cancer, may also increase AFP levels. Specific tumor markers that may lead to early detection of liver cancer are being studied.

  10. May 1, 2024 · Human α-fetoprotein (AFP) is a tumor-associated fetal mammalian glycoprotein involved in ontogenic and oncogenic growth. [1] . This tumor marker is encoded by the AFP gene on chromosome 4q25. [2] . The fetal protein is a 70-kDa single polypeptide chain containing 3% to 5% carbohydrate.

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