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2 days ago · This makes antibiotics the primary treatment avenue for sepsis. But bacteria can evolve to survive exposure to antibiotics, becoming resistant to the drugs commonly used to treat infections.
May 28, 2024 · Sepsis treatment usually requires hospitalization and the administration of intravenous (IV) antibiotics as quickly as possible. You will be monitored for progression into septic shock. If this happens, you will need additional treatments to fight the infection and keep blood flowing to all of your organs.
1 day ago · Westwood M, Ramaekers B, Whiting P, et al. Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis. Health Technol Assess. 2015;19(96):v-xxv, 1-236. (Meta-analysis; 18 studies)
May 13, 2024 · Importance Experimental and observational studies have suggested that empirical treatment for bacterial sepsis with antianaerobic antibiotics (eg, piperacillin-tazobactam) is associated with adverse outcomes compared with anaerobe-sparing antibiotics (eg, cefepime). However, a recent pragmatic clinical trial of piperacillin-tazobactam and ...
May 16, 2024 · Treatment with anti-anaerobic antibiotics was associated with fewer ventilator-free days, vasopressor free-days, and organ failure-free days. “Most patients with sepsis do not have a specific indication for anti-anaerobic antibiotics, and our study suggests they could cause real harm,” Rishi Chanderraj, MD, MSc, of the Ann Arbor Veterans ...
May 13, 2024 · Anti-anaerobic antibiotic treatment was associated with a 12% increase in 90-day mortality using a two-stage regression model (95% CI 3-21, P <0.001) and with a 14% increase in mortality using a ...
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May 13, 2024 · Critically ill patients frequently present with infection, potentially leading to sepsis or septic shock, where timely and appropriate antimicrobial treatment is paramount [1, 2]. We aim to provide a step-by-step approach for prescribing empirical antimicrobials in intensive care unit (ICU) patients with a suspected infection.
