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  1. Prompt diagnosis and treatment of acute promyelocytic leukemia (APL), the M3 subtype of acute myeloid leukemia (AML), is very important because people with APL can quickly develop life-threatening blood-clotting or bleeding problems if not treated.

  2. Apr 2, 2024 · Acute promyelocytic leukemia (APL) is a rare blood cancer that once was a fatal illness. Now, healthcare providers consider APL a curable disease, thanks to an innovative combination of chemotherapy and non-chemotherapy drugs.

  3. Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes.

  4. Acute promyelocytic leukemia (APL) is an aggressive type of acute myeloid leukemia (AML). It happens when there are too many of the blood-forming cells called promyelocytes in the blood and bone marrow.

  5. May 17, 2023 · APL is a type of leukemia caused by the uncontrolled proliferation of promyelocytes that are arrested in their normal maturation process. It is a subtype of acute myeloid leukemia (AML), but it has its own uniquely different disease mechanism, clinical manifestations and treatment.

  6. May 24, 2023 · Acute promyelocytic leukemia (APL) is a type of acute myeloid leukemia (AML). With proper treatment, the survival rates are high. APL is a relatively rare cancer, accounting for about 7–8% of...

  7. Jun 26, 2023 · Acute promyelocytic leukemia is a distinguished subset of acute myeloid leukemia which is characterized by fusion gene transcript PML-RAR-alpha and high cure rates with treatment.

  8. May 7, 2015 · Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML) in which cells in the bone marrow that produce blood cells (red cells, white cells and platelets) do not develop and function normally. APL begins with one or more acquired changes (mutations) to the DNA of a single blood-forming cell.

  9. Treatment for patients with acute promyelocytic leukemia (APL) differs from treatment for patients with other AML subtypes. Because of advances in diagnosis and treatment of this disease, APL is now considered the most curable form of adult leukemia.

  10. Acute promyelocytic leukemia (APL) is a rare cancer affecting the blood and bone marrow. It occurs primarily in middle-aged adults, but it also can affect children. Prompt diagnosis and treatment reduce symptoms long-term (remission) and often cure APL.

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