Search results
16 hours ago · To study the pharmacokinetics of ceftriaxone in plasma and lung tissue, ceftriaxone was administered as a single-dose monotherapy to neutropenic mice infected with S. pneumoniae. Moreover, we simulated humanized doses of ceftriaxone with the area under the concentration-time curve from 0 to 24 h (AUC 0–24) of blood drug concentration. The ...
3 days ago · Leptospirosis is a blood infection caused by the bacteria Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild ( headaches, muscle pains, and fevers) to severe ( bleeding in the lungs or meningitis ). [5] Weil's disease ( / ˈvaɪlz / VILES ), [12 ...
May 20, 2024 · Pediatrics. Group B streptococcal infection, also known as Group B streptococcal disease or just Group B strep infection, is the infectious disease caused by the bacterium Streptococcus agalactiae, which is the most common human pathogen belonging to the group B of the Lancefield classification of streptococci —hence the group B stretococcal ...
May 13, 2024 · Binds to the bacterial cell wall membrane, causing cell death. Therapeutic Effects: Bactericidal action against susceptible bacteria.Spectrum: similar to that of second-generation cephalosporins, but activity against staphylococci is less, while activity against gram-negative pathogens is greater, even for organisms resistant to first- and second-generation agents.
5 days ago · The data showed that in the micro-intent-to-treat population (n=744), zoliflodacin achieved a microbiological cure rate of 90.9%, a 5.3% difference compared to ceftriaxone and azithromycin, the current global standard of care, which achieved a 96.2% cure rate (95% CI: 1.4%, 8.7%).
May 16, 2024 · Ceftriaxone is also more effective than oral cephalosporins. In a meta-analysis of trials evaluating treatment of uncomplicated gonorrhea, higher cure rates were reported with ceftriaxone 250 mg than cefixime 400 mg (odds ratio [OR] 1.77, 95% CI 1.11-2.8) with equivalent side effects .
People also ask
How effective is ceftriaxone?
What is a high dose intramuscular (IM) ceftriaxone?
Why is ceftriaxone favored over other cephalosporins?
Is ceftriaxone a reliable treatment for macrolides?
4 days ago · Ceftriaxone. Adult: 500 mg, single IM dose (funded by endorsement on PSO or prescription, make up with 2 mL of 1% lignocaine) PLUS. Azithromycin. Adult: 1 g, single oral dose. OR. If confirmed chlamydia or gonorrhoea infection: Ceftriaxone. Adult: 1 g, single IM dose (funded by endorsement on PSO or prescription, make up with 3.5 mL of 1% ...
