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  2. 2 days ago · - Vỏ protein (vỏ capsit): Lớp vỏ bọc bên ngoài bộ gen được cấu tạo từ các capsome đóng vai trò bảo vệ.-Lớp vỏ ngoài: Cấu tạo từ lớp kép lipit và protein, bên trên có lớp gai protein. Lớp gai này sẽ thực hiện các nhiệm vụ của kháng nguyên, điển hình như giúp virus thâm ...

  3. May 14, 2024 · The fusion peptide of SARS-CoV-2 spike protein is functionally important for membrane fusion during virus entry and is part of a broadly neutralizing epitope. However, sequence determinants...

  4. 6 days ago · Coronaviruses are single-stranded linear RNA viruses consisting of a lipid membrane and four structural proteins: spike protein (S), membrane protein (M), envelope protein (E), and nucleocapsid protein (N) [ 4, 5 ].

  5. May 20, 2024 · Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion.

  6. May 16, 2024 · Mechanistic analysis reveals that the assembly of the spike protein into virus-like particles relies on interactions between the furin-cleaved spike protein and the membrane protein of SARS-CoV-2, suggesting a possible mechanism for furin activation.

  7. May 6, 2024 · Tan, T. K. et al. COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses. Nat. Commun ...

  8. 5 days ago · (structural protein) ORF5: Membrane (M) protein, virus assembly and budding (structural protein) ORF6: Enhances cellular DNA synthesis; Inhibits Type I IFN production and signaling ORF7a: Inhibits cellular protein synthesis; Induces inflammatory response by NF-kappaB and IL-8 promotor; Upregulate chemokines such as IL-8 and RANTES;

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