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1. www.mdpi.com › 2076/2607/12-6 › 1092Microorganisms | Free Full-Text | The Development of New ...

   www.mdpi.com › 2076/2607/12-6 › 1092

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   1 day ago · Dengue virus (DENV) poses a significant threat to global health, infecting approximately 390 million people annually. This virus comprises four serotypes capable of causing severe disease. Genetic analyses are crucial for understanding the epidemiology, evolution, and spread of DENV. Although previous studies have focused on the envelope protein-coding (E) gene, only a few primers can ...

2. bmcgenomics.biomedcentral.com › articles › 10DengueSeq: a pan-serotype whole genome amplicon sequencing ...

   bmcgenomics.biomedcentral.com › articles › 10

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   May 1, 2024 · Here, we present DengueSeq, an amplicon sequencing protocol, which enables whole-genome sequencing of all four dengue virus serotypes. We developed primer schemes for the four dengue virus serotypes, which can be combined into a pan-serotype approach.

3. People also ask

   What are the dynamics of dengue infection?

   • The dynamics of dengue infection is complex due to four co- circulating serotypes in many endemic areas, and the absence of long-term cross-immunity. The first large documented dengue outbreak occurred in Cuba in 1981 with more than 10000 severely affected persons and 158 deaths .

   Dynamic Epidemiological Models for Dengue Transmission: A ... - PLOS

   journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0049085&type=printable

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   What is the pathogenesis of dengue?

   • Symptomatic dengue illness is typically classified into dengue fever (DF), a self-limiting febrile illness, or a more severe form, dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). 2 Several hypotheses for the pathogenesis of dengue virus infection have been proposed.

   Long-term persistence of clinical symptoms in dengue-infected persons

   www.sciencedirect.com/science/article/pii/S1201971210025166

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   Do RNA and host factors modulate dengue virus replication and translation?

   • New methodologies have facilitated advances in our understanding of the RNA elements and viral and host factors that modulate dengue virus replication and translation. This review integrates research findings and explores future directions for research into the cellular and molecular mechanisms of dengue virus infection.

   Control of dengue virus translation and replication - PubMed

   pubmed.ncbi.nlm.nih.gov/19802575/

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4. www.cell.com › heliyon › fulltextDeep Learning Guided Prediction Modeling of Dengue Virus ...

   www.cell.com › heliyon › fulltext

   1 day ago · Evolution remains an incessant process in viruses, allowing them to elude the host immune response and induce severe diseases, impacting the diagnostic and vaccine effectiveness. Emerging and re-emerging diseases are among the significant public health concerns globally. The revival of dengue is mainly due to the potential for naturally arising mutations to induce genotypic alterations in ...

5. journals.plos.org › plosntds › articleDynamics of emergence and genetic diversity of dengue virus ...

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   May 20, 2024 · To characterize this epidemic with precision, we randomly sequenced and analyzed 336 samples of DENV2 during this period, including DENV2 sequences from 2017. Genotyping analysis revealed that the 2017–2020 epidemic was caused by a single DENV2 genotype, the genotype II cosmopolitan lineage (Figs 1B and 2B ).

6. Videos

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7. www.nature.com › articles › s41467/024/48465-0Human movement and environmental barriers shape the ... - Nature

   www.nature.com › articles › s41467/024/48465-0

   1 day ago · This database contains a mixture of case definitions with only Dengue Haemorrhagic Fever (DHF) reported 2000–2008, combined dengue and DHF 1995–1999 and 2009–2015, and combined non-severe ...

8. jamanetwork.com › journals › jamanetworkopenNeurological or Psychiatric Disorders After Dengue Fever

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   May 7, 2024 · Dengue fever, which has an estimated annual infection rate of up to 390 million, mainly affects Central and South America and Southeast Asia. 1, 2 Apart from possible direct invasion of dengue fever virus to the neurological system, the disease has been reported to be associated with neurological complications probably attributable to autoimmune...

9. elifesciences.org › articles › 90762Secreted dengue virus NS1 from infection is ... - eLife

   elifesciences.org › articles › 90762

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   5 days ago · (2017) The dengue virus non-structural protein 1 (NS1) is secreted from infected mosquito cells via a non-classical caveolin-1-dependent pathway The Journal of General Virology 98 :2088–2099. https://doi.org/10.1099/jgv.0.000881