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May 4, 2024 · Kuhn, R.J.; Zhang, W.; Rossmann, M.G.; Pletnev, S.V.; Corver, J.; Lenches, E.; Jones, C.T.; Mukhopadhyay, S.; Chipman, P.R.; Strauss, E.G.; et al. Structure of dengue virus: Implications for flavivirus organization, maturation, and fusion.
May 16, 2024 · Transmission. This disease is the most common mosquito-borne viral disease in humans. The virus is transmitted to humans through the bites of infected female mosquitoes. Aedes aegypti mosquito, a daytime feeder mosquito, is the primary vector. Transmission of dengue viral infection. Aedes albopictus is a secondary dengue vector.
May 20, 2024 · Several thousand clinical isolates and patient samples were collected from across the island and sequenced, resulting in 877 new genetic sequences of dengue virus. Our results show significant genetic diversity among dengue virus variants that circulated on the island over the past decade.
4 days ago · Data produced from numerous labs studying structure and function of flavivirus NS1 proteins provide diverse lines of evidence that the oligomeric state of NS1 is dynamic and can shift depending on context and environment. This means that the methodology used for NS1 production and purification will strongly impact the results of a study.
May 1, 2024 · DengueSeq was systematically evaluated with virus stocks and clinical specimens spanning the genetic diversity within each of the four dengue virus serotypes. The primer schemes can be plugged into existing amplicon sequencing workflows to facilitate the global need for expanded dengue virus genomic surveillance.
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May 2, 2024 · Figure 5.DENV serotype 4 maximum clade credibility tree, generated from 115 DENV-4 nucleotide sequences, showing emergence over time. Sequences are labeled by country of sample origin, indicated by colored circles, and include Nicaragua sequences (red) and publicly available sequences, as indicated.
May 15, 2024 · Dengue and severe dengue. Dengue is a mosquito-borne viral infection that is common in warm, tropical climates. Infection is caused by any one of four closely related dengue viruses (called serotypes) and these can lead to a wide spectrum of symptoms, including some which are extremely mild (unnoticeable) to those that may require medical ...
