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6 days ago · The FLiRT strains are subvariants of Omicron. One of them, KP.2, accounted for 28.2% of COVID infections in the United States by the third week of May, making it the dominant coronavirus variant in the country; another, KP.1.1, made up 7.1% of cases. Some experts have suggested that the new variants could cause a summer surge in COVID cases.
May 15, 2024 · Here, we provide evidence that the SARS-CoV-2 envelope (E) protein initiates innate immune inflammation, via toll-like receptor 2 signaling, and establishes a sustained state of innate immune tolerance following initial activation.
May 15, 2024 · Coronaviruses have enveloped virions that measure approximately 120 nm in diameter. The genome consists of a single strand of positive-sense RNA (ribonucleic acid). Examples of coronaviruses include the agents that cause SARS, MERS, and COVID-19.
- The Editors of Encyclopaedia Britannica
- What is a coronavirus?Coronavirus is any virus belonging to the family Coronaviridae. Club-shaped glycoprotein spikes in the envelope give the viruses a crownlike, or co...
- What diseases are caused by coronaviruses?Coronaviruses cause SARS (severe acute respiratory syndrome), MERS (Middle East respiratory syndrome), and COVID-19 (coronavirus disease 2019). The...
- Does the virus that causes COVID-19 belong to the coronavirus family?The virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the coronavirus family and is closely related to the SARS c...
May 20, 2024 · Coronaviruses use a very diverse range of receptors; SARS-CoV (which causes SARS) and SARS-CoV-2 (which causes COVID-19) both interact with angiotensin-converting enzyme 2 (ACE2). The S2 region contains the fusion peptide and other fusion infrastructure necessary for membrane fusion with the host cell, a required step for infection and viral ...
May 13, 2024 · Two of these mutations—456 and 346—eliminate binding sites for antibodies that neutralize SARS-CoV-2. However, those same antibody binding sites are also important for the virus to bind to and enter cells. So in evading antibodies, these FLiRT variants may have also lost some ability to bind to their receptor.
May 4, 2024 · The large enveloped virus SARS-CoV-2 with a single-stranded RNA genome prone to rapid mutation with a positive sense of approximately 29.9 kb in length, is a member of the...
4 days ago · The virus severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, is the causative agent of the current COVID-19 pandemic. It possesses a large 30 kilobase (kb) genome that encodes structural, non-structural, and accessory proteins. Although not necessary to cause disease, these accessory proteins are known to influence viral replication ...
