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  1. May 17, 2024 · The incidence of bacterial sepsis ranges from 1 to 10 cases per 1,000 live births, with a 4-fold to 10-fold increase in preterm neonates (1)(2)(3)(4). Despite the significant progress in neonatal care, sepsis remains a leading cause of morbidity and mortality in Neonatal Intensive Care Units (NICUs), accounting for 243,000 deaths per year ...

  2. Apr 30, 2024 · The most important risk factor causing sepsis development in the neonatal period is premature birth and low birth weight. Premature babies with low birth weight have a risk of developing sepsis three to ten times higher than full-term babies with normal birth weight.

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  4. 16 hours ago · We identified 1209 eligible sepsis huddles among 604 infants. There were 111 culture-confirmed LOI episodes (9% of all huddles). Twelve clinical signs of infection poorly distinguished infants with and without LOI, with sensitivity for each ranging from 2 to 36% and AUROC ranging 0.49-0.53.

  5. May 17, 2024 · Premature (“preemie”) babies may differ in their growth and development compared to full-term babies. But every baby, whether premature or full-term, follows their own developmental timeline, says Liz Smith, APRN-NP , neonatal nurse practitioner at Lurie Children’s.

  6. May 2, 2024 · Although RDS is generally a disease of preterm neonates, it can develop in term newborns, especially with sepsis, pneumonia, or meconium aspiration. In these cases, surfactant can be inactivated by inflammation and/or the presence of meconium ( Chap. 33 , p. 600).

  7. May 20, 2024 · Resident and Family Guide to Understanding Sepsis. The Health Quality Innovation Network’s Resident and Family Guide to Understanding Sepsis defines what sepsis is and who is at risk of getting sepsis. This guide also describes the signs and symptoms of sepsis and what family members can do if they suspect a loved one may have sepsis.

  8. May 2, 2024 · Diagnosing sepsis remains problematic. Pathogen identification is frequently lacking and the dysregulated host response is non-specific. Blood cultures often take days to deliver a result and, even then, approximately 90% are negative, sometimes despite strong clinical evidence of sepsis.

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