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  2. May 12, 2024 · In the current pre-specified analysis from the Pragmatic Urinary Sodium-based algoritHm in Acute Heart Failure (PUSH-AHF) trial, we investigated the association between (worsening) renal function, outcomes and the effect of intensive natriuresis-guided loop diuretic therapy as compared with standard of care (SOC).

  3. May 29, 2024 · Pharmacology. Chemistry. History. Society and culture. Research. References. Spironolactone. Not to be confused with Spirolactone. Spironolactone 25 mg. Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. [4] .

  4. 2 days ago · Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. The actions of metolazone result from interference with the renal tubular mechanism of electrolyte reabsorption.

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  5. May 13, 2024 · In patients with obesity-related HFpEF, semaglutide improved heart failure-related symptoms and physical limitations across diuretic use subgroups, with more pronounced benefits among patients receiving loop diuretics at baseline.

  6. May 24, 2024 · Diuretics. Diuretics, also called water pills, help the body get rid of excess salt and water. This helps control blood pressure. They are often used with other medications. Commonly prescribed diuretics include: Furosemide (Lasix) Bumetanide (Bumex) Torsemide (Demadex) Chlorothiazide (Diuril) Amiloride (Midamor Chlorthalidone, Hygroton)

  7. May 16, 2024 · Mechanism of Action. Dofetilide shows Vaughan Williams Class III antiarrhythmic activity. The mechanism of action is blockade of the cardiac ion channel carrying the rapid component of the delayed rectifier potassium current, I Kr.

  8. May 31, 2024 · Diuretic, any drug that increases the flow of urine. Diuretics promote the removal from the body of excess water, salts, poisons, and accumulated metabolic products, such as urea. They serve to rid the body of excess fluid that accumulates in the tissues owing to various disease states.

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