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  1. May 4, 2024 · Neonatal sepsis is a clinical syndrome of systemic illness accompanied by bacteremia occurring in the first month of life. It can be classified into 2 relatively distinct syndromes based on the age of presentation: early-onset and late-onset sepsis. These 2 entities will be discussed separately. + + +

  2. May 20, 2024 · Sepsis represents the most severe contributor to neonatal mortality, with 99% of global neonatal mortality occurring within low- and middle-income countries (LMICs) 2,3,4.

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  4. May 10, 2024 · Identifying and treating sepsis early is key to saving lives. Following are the sepsis definitions and treatment guidelines to help frame your approach to critically ill patients who have a suspected or confirmed diagnosis of sepsis.

  5. 2 days ago · We identified 1209 eligible sepsis huddles among 604 infants. There were 111 culture-confirmed LOI episodes (9% of all huddles). Twelve clinical signs of infection poorly distinguished infants with and without LOI, with sensitivity for each ranging from 2 to 36% and AUROC ranging 0.49-0.53.

  6. May 7, 2024 · View PDF View EPUB. Background. Neonatal sepsis is the third leading cause of mortality during the neonatal period, with manifestations atypical and obscure. But the gold standard-blood culture test, requiring 3–5 days, makes it difficult to unveil the final pathogen and leads to the increasing ratio of false-negative results.

  7. May 20, 2024 · Epidemiology of neonatal infections in hospitals of Nepal: evidence from a large- scale study [2020] BMC Infectious Diseases. Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal [2020] Netherlands. Acta Paediatrica.

  8. May 10, 2024 · Gram-negative bacteria (GNB) are a major cause of neonatal sepsis in low- and middle-income countries (LMICs). Although the World Health Organization (WHO) reports that over 80% of these sepsis ...

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