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3 days ago · Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
May 10, 2024 · Detection of GBS DNA in the placenta is associated with neonatal unit admission, infant morbidity and, in some cases, sepsis and foetal cytokine storm. Francesca Gaccioli. Katie Stephens. Gordon C ...
May 22, 2024 · Neonatal sepsis is a systemic inflammatory response syndrome in the presence of infection during the first 28 days of life and includes septicemia, pneumonia, meningitis, arthritis, osteomyelitis, and a urinary tract infection [ 1, 2 ].
May 28, 2024 · Because early sepsis recognition and timely antibiotic administration appear to improve outcomes in neonatal and pediatric sepsis(5,6), LOI evaluations are frequently initiated in the setting of clinical illness, with most infants ultimately found to be uninfected(7–10). The clinical presentation of neonatal LOI is often nonspecific and
May 28, 2024 · We identified 1209 eligible sepsis huddles among 604 infants. There were 111 culture-confirmed LOI episodes (9% of all huddles). Twelve clinical signs of infection poorly distinguished infants with and without LOI, with sensitivity for each ranging from 2 to 36% and AUROC ranging 0.49-0.53.
May 20, 2024 · Neonatal infection represents a significant cause of childhood mortality, potentially accounting for over a third of all global neonatal deaths 1.Sepsis represents the most severe contributor to ...
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6 days ago · Neonatal sepsis: current insights and challenges The incidence of bacterial sepsis ranges from 1 to 10 cases per 1,000 live births, with a 4-fold to 10-fold increase in preterm neonates (1–4). Despite the significant progress in neonatal care, sepsis remains a leading cause of morbidity and mortality in Neonatal
