Search results
Nov 12, 2020 · Treatment for Chagas disease focuses on killing the parasite and managing signs and symptoms. During the acute phase of Chagas disease, the prescription medications benznidazole and nifurtimox (Lampit) may be of benefit. Both drugs are available in the regions most affected by Chagas disease.
Nov 21, 2019 · Both benznidazole and nifurtimox are better tolerated in children than in adults. 22,23 In adults, it is difficult to draw valid drug tolerance comparisons from the scientific literature, considering disparities in study settings and designs, drug dosages, treatment durations and methods of observation of tolerance.
May 16, 2022 · The only two treatments currently available (benznidazole, generally the first choice, and nifurtimox) date from the 1960s and are poorly tolerated.
[8] [9] Due to the low tolerance and completion rate of nifurtimox, benznidazole is now being more considered for those who have Chagas disease and require long-term treatment. [5] [9]
Apr 4, 2024 · Chagas disease can be treated with benznidazole or nifurtimox. Both medicines kill the parasite and are fully effective in curing the disease if given early in the acute phase, including in case of congenital transmission.
Jun 30, 2011 · The only currently available drugs with proven efficacy against T. cruzi are nifurtimox and benznidazole, 1,17–19 which were developed empirically in the late 1960s and early 1970s, respectively ...
Oct 10, 2016 · Nifurtimox is 1 of only 2 medications available for treating Chagas disease (CD) and currently the only drug available in the United States, but its safety and tolerance have not been extensively studied. This is the first study to evaluate tolerance of nifurtimox in US patients with CD. Methods.
