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  2. 3 days ago · 11570 Background: Synovial sarcoma (SS) is a rare, slow growing, and aggressive soft tissue sarcoma that commonly affects young adults, with a diagnosis at an average age of 30 years. It usually originates near the joints of the extremities and presents as a painless lump. Metastasis to the regional lymph nodes and lungs is common. SS is proposed to be a result of a chromosomal translocation ...

  3. 2 days ago · Sarcoma research at MD Anderson goes beyond these presentations at ASCO. For example, Dejka Araujo, M.D., professor of Sarcoma Medical Oncology, and her colleagues recently published findings in The Lancet of a clinical trial of the first T cell therapy for patients with metastatic or unresectable synovial sarcoma or myxoid round cell ...

  4. May 11, 2024 · Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location, means that...

  5. May 8, 2024 · Synovial sarcoma (SS) is a malignant sarcoma of young adults, rarely involving the head and neck, especially the principal salivary glands. According to Setti et al., soft tissue tumors account for 2-5% of salivary gland tumors [1].

  6. May 10, 2024 · Synovial sarcoma (SS) is a malignant tumor comprising 5–10% of all soft tissue sarcomas. SS has distinct characteristics, such as a predilection for young adults and relatively slow growth compared to other soft tissue sarcomas.

  7. May 14, 2024 · Synovial sarcoma (SyS) is an aggressive soft-tissue malignancy characterized by a pathognomonic chromosomal translocation leading to the formation of the SS18::SSX fusion oncoprotein. SS18::SSX associates with mammalian BAF complexes suggesting deregulation of chromatin architecture as the oncogenic driver in this tumour type.

  8. May 23, 2024 · Sarcoma. Immunotherapy in Sarcoma: Current Data and Promising Strategies. Georgina E. Wood, MD, PhD1; Christian Meyer, MD2; Florent Petitprez, PhD3; and Sandra P. D’Angelo, MD4. DOI https://doi.org/10.1200/EDBK_432234. OVERVIEW. Accepted March 27, 2024 Published May 23, 2024.

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